Molecular structure of Azadirachtin, CAS Number: 11141-17-6
Azadirachtin (CAS 11141-17-6)
Alternate Names:
Bioneem
Application:
Azadirachtin is a highly oxidized tetranortriterpenoid
CAS Number:
11141-17-6
Purity:
≥95%
Molecular Weight:
720.71
Molecular Formula:
C35H44O16
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Azadirachtin is a limonoid compound that is found in the seeds of the neem tree (Azadirachta indica) and is primarily used in agricultural research as a potent biopesticide. It is studied for its ability to disrupt the life cycle of insects, acting as an antifeedant, growth inhibitor, and oviposition deterrent. Research on azadirachtin focuses on its modes of action, which include inhibiting the synthesis and release of molting hormones, thereby preventing the maturation of larvae and affecting the reproductive cycle of pests. Further studies investigate the potential for azadirachtin to serve as an environmentally friendly pesticide alternative, due to its biodegradability and low toxicity to non-target organisms. Azadirachtin is also of interest for its potential to induce systemic acquired resistance in plants, enhancing their defensive capacity against a broad spectrum of pests.
Azadirachtin (CAS 11141-17-6) References
- Azadirachtin interacts with retinoic acid receptors and inhibits retinoic acid-mediated biological responses. | Thoh, M., et al. 2013. J Biol Chem. 288: 8563. PMID: 23526249
- Azadirachtin-induced apoptosis involves lysosomal membrane permeabilization and cathepsin L release in Spodoptera frugiperda Sf9 cells. | Wang, Z., et al. 2015. Int J Biochem Cell Biol. 64: 126-35. PMID: 25849458
- Azadirachtin acting as a hazardous compound to induce multiple detrimental effects in Drosophila melanogaster. | Zhang, J., et al. 2018. J Hazard Mater. 359: 338-347. PMID: 30048948
- Azadirachtin impairs egg production in Atta sexdens leaf-cutting ant queens. | Amaral, KD., et al. 2018. Environ Pollut. 243: 809-814. PMID: 30243189
- Production of biopesticide azadirachtin using plant cell and hairy root cultures. | Thakore, D. and Srivastava, AK. 2017. Eng Life Sci. 17: 997-1005. PMID: 32624850
- Azadirachtin interferes with basal immunity and microbial homeostasis in the Rhodnius prolixus midgut. | Vieira, CS., et al. 2021. Dev Comp Immunol. 114: 103864. PMID: 32918931
- Deleterious action of azadirachtin against the mutualistic fungus of leaf-cutting ants. | Amaral, KD., et al. 2020. J Basic Microbiol. 60: 931-937. PMID: 33135277
- Azadirachtin downregulates the expression of the CREB gene and protein in the brain and directly or indirectly affects the cognitive behavior of the Spodoptera litura fourth-instar larvae. | Qin, D., et al. 2021. Pest Manag Sci. 77: 1873-1885. PMID: 33284470
- Treating green pea aphids, Myzus persicae, with azadirachtin affects the predatory ability and protective enzyme activity of harlequin ladybirds, Harmonia axyridis. | Qin, D., et al. 2021. Ecotoxicol Environ Saf. 212: 111984. PMID: 33517036
- Identification of azadirachtin responsive genes in Spodoptera frugiperda larvae based on RNA-seq. | Shu, B., et al. 2021. Pestic Biochem Physiol. 172: 104745. PMID: 33518039
- Effects of sublethal azadirachtin on the immune response and midgut microbiome of Apis cerana cerana (Hymenoptera: Apidae). | Zhao, K., et al. 2022. Ecotoxicol Environ Saf. 229: 113089. PMID: 34929506
- Azadirachtin Attenuates Lipopolysaccharide-Induced ROS Production, DNA Damage, and Apoptosis by Regulating JNK/Akt and AMPK/mTOR-Dependent Pathways in Rin-5F Pancreatic Beta Cells. | John, A. and Raza, H. 2021. Biomedicines. 9: PMID: 34944759
- Metabolic Changes in Larvae of Predator Chrysopa sinica Fed on Azadirachtin-Treated Plutella xylostella Larvae. | Zhang, P., et al. 2022. Metabolites. 12: PMID: 35208232
- Effects of azadirachtin on detoxification-related gene expression in the fat bodies of the fall armyworm, Spodoptera frugiperda. | Yu, H., et al. 2022. Environ Sci Pollut Res Int.. PMID: 35294689
- Azadirachtin inhibits the development and metabolism of the silk glands of Spodoptera frugiperda and affects spinning behavior. | Zhao, W., et al. 2022. Pest Manag Sci. 78: 5293-5301. PMID: 36053871
Inhibitor of:
TIAR, Timm8a2, TISP74, and TMEM216.Activator of:
fushi tarazu.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Azadirachtin, 1 mg | sc-257105 | 1 mg | $174.00 | |||
Azadirachtin, 5 mg | sc-257105A | 5 mg | $367.00 | |||
Azadirachtin, 10 mg | sc-257105B | 10 mg | $614.00 | |||
Azadirachtin, 25 mg | sc-257105C | 25 mg | $979.00 | |||
Azadirachtin, 50 mg | sc-257105D | 50 mg | $1693.00 |