Molecular structure of Isoquinoline, CAS Number: 119-65-3
Isoquinoline (CAS 119-65-3)
CAS Number:
119-65-3
Molecular Weight:
129.16
Molecular Formula:
C9H7N
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Isoquinoline is a heterocyclic compound that functions as a building block in the synthesis of various organic compounds. It acts as a precursor in the production of agrochemicals, and dyes. Its mode of action involves participating in a variety of chemical reactions, including cyclization, oxidation, and reduction processes. Isoquinoline can serve as a ligand in coordination chemistry, forming complexes with transition metals. It exhibits potential as a fluorescent probe in biological imaging studies due to its unique photophysical properties. At the molecular level, isoquinoline interacts with other compounds to form new chemical entities with diverse applications in development. Its versatile nature allows for the exploration of novel pathways and the discovery of innovative chemical structures.
Isoquinoline (CAS 119-65-3) References
- Decomposition of isoquinoline and quinoline by supercritical water. | Ogunsola, OM. 2000. J Hazard Mater. 74: 187-95. PMID: 10794913
- Construction of indole- and isoquinoline-fused nitrogen-containing heterocycles through copper-catalyzed multi-component reaction. | Ohta, Y. 2010. Yakugaku Zasshi. 130: 925-36. PMID: 20606372
- Isoquinoline alkaloids and their binding with DNA: calorimetry and thermal analysis applications. | Bhadra, K. and Kumar, GS. 2010. Mini Rev Med Chem. 10: 1235-47. PMID: 20716060
- Isoquinoline derivatives as potent CRTH2 antagonists: design, synthesis and SAR. | Nishikawa-Shimono, R., et al. 2013. Bioorg Med Chem. 21: 7674-85. PMID: 24216094
- Isoquinoline derivatives as potent, selective, and orally active CRTH2 antagonists. | Nishikawa-Shimono, R., et al. 2014. Chem Pharm Bull (Tokyo). 62: 528-37. PMID: 24881658
- Isolation of microorganisms capable of degrading isoquinoline under aerobic conditions. | Aislabie, J., et al. 1989. Appl Environ Microbiol. 55: 3247-9. PMID: 2515806
- Isoquinoline is a possible anti-psoriatic agent in coal tar. | Foreman, MI., et al. 1985. Br J Dermatol. 112: 323-8. PMID: 2579670
- Effects of newly synthetized isoquinoline derivatives on rat uterine contractility and ROCK II activity. | Domokos, D., et al. 2018. Bioorg Med Chem Lett. 28: 466-469. PMID: 29269216
- Discovery of 4,6- and 5,7-Disubstituted Isoquinoline Derivatives as a Novel Class of Protein Kinase C ζ Inhibitors with Fragment-Merging Strategy. | Atobe, M., et al. 2020. J Med Chem. 63: 7143-7162. PMID: 32551607
- Fungally Derived Isoquinoline Demonstrates Inducer-Specific Tau Aggregation Inhibition. | Ingham, DJ., et al. 2021. Biochemistry. 60: 1658-1669. PMID: 34009955
- Benzylated Dihydroflavones and Isoquinoline-Derived Alkaloids from the Bark of Diclinanona calycina (Annonaceae) and Their Cytotoxicities. | Costa, EV., et al. 2021. Molecules. 26: PMID: 34207059
- Synthesis and SAR Studies of Isoquinoline and Tetrahydroisoquinoline Derivatives as Melatonin Receptor Ligands. | Ettaoussi, M., et al. 2022. ChemMedChem. 17: e202100658. PMID: 34797951
- Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus Aspergillus puniceus. | Liu, CM., et al. 2022. Mar Drugs. 20: PMID: 35049933
- Natural isoquinoline alkaloids: Pharmacological features and multi-target potential for complex diseases. | Plazas, E., et al. 2022. Pharmacol Res. 177: 106126. PMID: 35151857
- Bioactivity and In Silico Studies of Isoquinoline and Related Alkaloids as Promising Antiviral Agents: An Insight. | Sharma, D., et al. 2022. Biomolecules. 13: PMID: 36671402
Inhibitor of:
INTS3, LOC646576, Naglt1a, RBMY1, and ZCCHC7.Activator of:
1300002E11Rik, CARD 10, DARPP-32, GLCCI1, Olr808, Olr83, Olr832, Olr838, Olr851, Olr87, Olr889, Olr92, PAGE-4, RBM12, RBM41, SFRS11, SFRS17A, SLC37A3, and TAF II p70.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isoquinoline, 5 g | sc-255224 | 5 g | $26.00 | |||
Isoquinoline, 100 g | sc-255224A | 100 g | $58.00 |