Molecular structure of 2-Methylindole, CAS Number: 95-20-5
2-Methylindole (CAS 95-20-5)
Alternate Names:
2-Methyl-1H-indole
Application:
2-Methylindole is a reactant for Friedel-Crafts alkylation reactions
CAS Number:
95-20-5
Purity:
>98%
Molecular Weight:
131.17
Molecular Formula:
C9H9N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
2-Methylindole is a reactant for regioselective synthesis of oxopyrrolidine analogs via iodine-catalyzed Markovnikov addition reaction, Friedel-Crafts alkylation reactions, and Michael addition reactions. 2-Methylindole is an intermediate in the synthesis of indole derivative with potential antifungal activities. This compound is used as a starting material for the synthesis of various organic compounds such as dyes and polymers.
2-Methylindole (CAS 95-20-5) References
- Nature of non-radiative processes involved in the excited state of 9-cyanoanthracene in presence of 2-methylindole/2-methylindoline quenchers. A laser flash photolysis study to reveal the medium effects. | Misra, T., et al. 2002. Spectrochim Acta A Mol Biomol Spectrosc. 58: 1631-41. PMID: 12166735
- Adsorption of indole and 2-methylindole on ligand-exchange matrix. | Erciyes, N., et al. 2004. J Colloid Interface Sci. 278: 91-5. PMID: 15313641
- The reaction of indole with the aminoacrylate intermediate of Salmonella typhimurium tryptophan synthase: observation of a primary kinetic isotope effect with 3-[(2)H]indole. | Cash, MT., et al. 2004. Arch Biochem Biophys. 432: 233-43. PMID: 15542062
- Indole ring oxidation by activated leukocytes prevents the production of hypochlorous acid. | Ximenes, VF., et al. 2005. Braz J Med Biol Res. 38: 1575-83. PMID: 16258625
- Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon. | Rajeshwaran, GG. and Mohanakrishnan, AK. 2011. Org Lett. 13: 1418-21. PMID: 21341756
- 2-Methylindole as an indicative nucleophile for developing a three-component reaction of aldehyde with two different nucleophiles. | Jiang, D., et al. 2014. ACS Comb Sci. 16: 287-92. PMID: 24555774
- Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists. | Brown, DR., et al. 2015. Environ Sci Pollut Res Int. 22: 8329-38. PMID: 25532870
- Synthesis of Quinoline-Fused 1-Benzazepines through a Mannich-Type Reaction of a C,N-Bisnucleophile Generated from 2-Aminobenzaldehyde and 2-Methylindole. | Min, L., et al. 2016. Org Lett. 18: 364-7. PMID: 26757343
- Spectroscopic study of 2-methylindole and 3-methylindole: Solvents interactions and DFT studies. | Popoola, SA. 2018. Spectrochim Acta A Mol Biomol Spectrosc. 189: 578-585. PMID: 28881283
- Transition-Metal-Free Coupling Reaction of Dithiocarbamates with Indoles: C-S Bond Formation. | Halimehjani, AZ., et al. 2018. J Org Chem. 83: 5778-5783. PMID: 29693382
- Homogeneously-catalysed hydrogen release/storage using the 2-methylindole/2-methylindoline LOHC system in molten salt-organic biphasic reaction systems. | Søgaard, A., et al. 2019. Chem Commun (Camb). 55: 2046-2049. PMID: 30687857
- Dehydrogenation of the liquid organic hydrogen carrier system 2-methylindole/2-methylindoline/2-methyloctahydroindole on Pt(111). | Bachmann, P., et al. 2019. J Chem Phys. 151: 144711. PMID: 31615244
- Antibiofilm and Antivirulence Properties of Indoles Against Serratia marcescens. | Sethupathy, S., et al. 2020. Front Microbiol. 11: 584812. PMID: 33193228
- Preparation and evaluation a mixed-mode stationary phase with C18 and 2-methylindole for HPLC. | Hosseini, ES. and Tabar Heydar, K. 2021. Biomed Chromatogr. 35: e5068. PMID: 33450065
- Copper-catalyzed multicomponent reactions for the efficient synthesis of diverse spirotetrahydrocarbazoles. | Zhan, SC., et al. 2022. Beilstein J Org Chem. 18: 796-808. PMID: 35875709
Inhibitor of:
EG546335.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Methylindole, 25 g | sc-254280 | 25 g | $32.00 |