Sinapic acid (CAS 530-59-6)
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Sinapic acid, a phenolic acid abundantly present in plants and a prominent constituent of mustard seed oil, holds significance as a vital metabolite in plant systems. It actively participates in diverse metabolic pathways, contributing to the synthesis of lignin, flavonoids, and other phenolic compounds. Also known as 2-hydroxy-3,5-dimethoxybenzoic acid, sinapic acid emerges as a derivative of benzoic acid, adding to its chemical identity. Remarkably, sinapic acid exhibits a broad spectrum of action, targeting various cellular components. Notably, it has been found to hinder the activity of enzymes involved in the production of pro-inflammatory mediators, such as cyclooxygenase-2 and inducible nitric oxide synthase. This inhibition offers potential anti-inflammatory benefits. Additionally, sinapic acid has demonstrated the ability to impede the activity of enzymes responsible for generating pro-angiogenic mediators, including vascular endothelial growth factor and platelet-derived growth factor.
Sinapic acid (CAS 530-59-6) References
- Sinapic Acid Promotes Browning of 3T3-L1 Adipocytes via p38 MAPK/CREB Pathway. | Bae, IS. and Kim, SH. 2020. Biomed Res Int. 2020: 5753623. PMID: 32351999
- Sinapic acid attenuates cisplatin-induced nephrotoxicity through peroxisome proliferator-activated receptor gamma agonism in rats. | Singh, HP., et al. 2020. J Pharm Bioallied Sci. 12: 146-154. PMID: 32742113
- Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats. | Altındağ, F., et al. 2021. Food Chem Toxicol. 156: 112443. PMID: 34329744
- Sinapic Acid Alleviated Inflammation-Induced Intestinal Epithelial Barrier Dysfunction in Lipopolysaccharide- (LPS-) Treated Caco-2 Cells. | Lan, H., et al. 2021. Mediators Inflamm. 2021: 5514075. PMID: 34539242
- Sinapic Acid Controls Inflammation by Suppressing NLRP3 Inflammasome Activation. | Lee, EH., et al. 2021. Cells. 10: PMID: 34571975
- Sinapic acid ameliorates cardiac dysfunction and cardiomyopathy by modulating NF-κB and Nrf2/HO-1 signaling pathways in streptozocin induced diabetic rats. | Raish, M., et al. 2022. Biomed Pharmacother. 145: 112412. PMID: 34768051
- Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway. | Huang, Z., et al. 2022. Drug Dev Res. 83: 721-734. PMID: 34859906
- Sinapic acid ameliorates paracetamol-induced acute liver injury through targeting oxidative stress and inflammation. | Rostami, A., et al. 2022. Mol Biol Rep. 49: 4179-4191. PMID: 35279777
- Sinapic acid attenuates muscle atrophy in streptozotocin-induced diabetic mice. | Xianchu, L., et al. 2021. Iran J Basic Med Sci. 24: 1695-1701. PMID: 35432808
- Dietary sinapic acid attenuated high-fat diet-induced lipid metabolism and oxidative stress in male Syrian hamsters. | Wang, K., et al. 2022. J Food Biochem. 46: e14203. PMID: 35470867
- Sinapic Acid Ameliorates REV-ERB α Modulated Mitochondrial Fission against MPTP-Induced Parkinson's Disease Model. | Lee, SB. and Yang, HO. 2022. Biomol Ther (Seoul). 30: 409-417. PMID: 35611585
- Sinapic acid restores blood parameters, serum antioxidants, and liver and kidney functions in obesity. | Koriem, KMM. and Gad, IB. 2022. J Diabetes Metab Disord. 21: 293-303. PMID: 35673480
- Sinapic Acid Ameliorates Acetic Acid-Induced Ulcerative Colitis in Rats by Suppressing Inflammation, Oxidative Stress, and Apoptosis. | Shahid, M., et al. 2022. Molecules. 27: PMID: 35807383
- Sinapic acid ameliorates airway inflammation in murine ovalbumin-induced allergic asthma by reducing Th2 cytokine production. | Saeedavi, M., et al. 2022. Life Sci. 307: 120858. PMID: 35931198
- Dietary Sinapic Acid Alleviates Adiposity and Inflammation in Diet-Induced Obese Mice. | Yoon, HJ., et al. 2022. Prev Nutr Food Sci. 27: 407-413. PMID: 36721747
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Sinapic acid, 1 g | sc-253564 | 1 g | $53.00 |