Date published: 2025-11-2

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Imidazolidinyl urea (CAS 39236-46-9)

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Alternate Names:
N,N′-Methylenebis[N′-[3-(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl]-urea; Imidurea
Application:
Imidazolidinyl urea is an antimicrobial preservative
CAS Number:
39236-46-9
Purity:
98%
Molecular Weight:
388.29
Molecular Formula:
C11H16N8O8
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Imidazolidinyl urea, a nitrogen-containing heterocyclic compound, has garnered considerable attention in scientific research due to its distinctive properties and diverse biological activities. It is compromised of an imidazole ring, a five-membered ring system with two nitrogen atoms, and a urea group, a carbonyl-containing heterocyclic compound. Imidazolidinyl urea has been harnessed across a multitude of scientific research applications. In vitro studies have employed Imidazolidinyl urea to explore the impact of various hormones and enzymes on cellular processes.


Imidazolidinyl urea (CAS 39236-46-9) References

  1. Characterization and chemistry of imidazolidinyl urea and diazolidinyl urea.  |  Lehmann, SV., et al. 2006. Contact Dermatitis. 54: 50-8. PMID: 16426294
  2. Imidazolidinyl urea (Germall 115) should be patch tested in water.  |  van Neer, PA. and van der Kley, AM. 1991. Contact Dermatitis. 24: 302. PMID: 1868721
  3. Hydrogel allergic contact dermatitis and imidazolidinyl urea/diazolidinyl urea.  |  Carvalho, R., et al. 2011. Cutan Ocul Toxicol. 30: 331-2. PMID: 21425953
  4. Characterization of the decomposition of compounds derived from imidazolidinyl urea in cosmetics and patch test materials.  |  Doi, T., et al. 2012. Contact Dermatitis. 67: 284-92. PMID: 22564140
  5. Cell chip-based monitoring of toxic effects of cosmetic compounds on skin fibroblast cells.  |  An, JH., et al. 2012. J Nanosci Nanotechnol. 12: 5143-8. PMID: 22966535
  6. Contact Dermatitis to Medications and Skin Products.  |  Nguyen, HL. and Yiannias, JA. 2019. Clin Rev Allergy Immunol. 56: 41-59. PMID: 30145645
  7. Dose-response sensitization experiments with imidazolidinyl urea.  |  Ziegler, V., et al. 1988. Contact Dermatitis. 19: 236-7. PMID: 3191694
  8. Construction of supramolecular hydrogels using imidazolidinyl urea as hydrogen bonding reinforced factor.  |  Yu, J., et al. 2020. J Mater Chem B. 8: 3058-3063. PMID: 32201874
  9. Imidazolidinyl urea activates mast cells via MRGPRX2 to induce non-histaminergic allergy.  |  Gao, J., et al. 2021. Toxicol Res (Camb). 10: 467-475. PMID: 34141160
  10. Imidazolidinyl urea (germall 115) causing cosmetic dermatitis.  |  O'Brien, TJ. 1987. Australas J Dermatol. 28: 36-7. PMID: 3426483
  11. The development of dual-function solid-phase method as extraction and a decomposition reaction media for the determination of a formaldehyde releaser, imidazolidinyl urea, in cosmetics.  |  Doi, T., et al. 2022. Anal Chim Acta. 1191: 338891. PMID: 35033244
  12. Hidden contact allergy to formaldehyde in imidazolidinyl urea.  |  de Groot, AC. and Weyland, JW. 1987. Contact Dermatitis. 17: 124-5. PMID: 3652704
  13. Addition of formaldehyde releaser imidazolidinyl urea and MOPS buffer to urine samples enables delayed processing for flow cytometric analysis of urinary cells: A simple, two step conservation method of urinary cells for flow cytometry.  |  Freund, P., et al. 2023. Cytometry B Clin Cytom.. PMID: 36880455
  14. Multisampling-based docking reveals Imidazolidinyl urea as a multitargeted inhibitor for lung cancer: an optimisation followed multi-simulation and in-vitro study.  |  Ahmad, S., et al. 2023. J Biomol Struct Dyn. 1-18. PMID: 37154501

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Imidazolidinyl urea, 25 g

sc-252901
25 g
$51.00

Imidazolidinyl urea, 100 g

sc-252901A
100 g
$140.00

Imidazolidinyl urea, 500 g

sc-252901B
500 g
$400.00

Imidazolidinyl urea, 1 kg

sc-252901C
1 kg
$700.00