Date published: 2025-11-3

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Aleuritic acid (CAS 533-87-9)

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Alternate Names:
DL-threo-9,10,16-Trihydroxypalmitic acid
Application:
Aleuritic acid is an abundant source of prostanoid synthons
CAS Number:
533-87-9
Purity:
≥94%
Molecular Weight:
304.42
Molecular Formula:
C16H32O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Aleuritic acid is an abundant source of prostanoid synthons. Aleuritic acid is a naturally occurring fatty acid that is present in human milk, bovine milk, and other animal sources. It plays a significant role in human milk fat and possesses diverse biological activities. Although the precise mechanism of action of DHHA remains incompletely understood, studies indicate that it can operate through various means, including impeding pro-inflammatory cytokines and initiating apoptosis. Furthermore, DHHA has been observed to regulate the expression of multiple genes involved in cell growth and differentiation.


Aleuritic acid (CAS 533-87-9) References

  1. New reagents for the introduction of reactive functional groups into chemically synthesized DNA probes.  |  Skrzypczynski, Z. and Wayland, S. 2003. Bioconjug Chem. 14: 642-52. PMID: 12757390
  2. Aleuritic (9,10,16-trihydroxypalmitic) acid self-assembly on mica.  |  Heredia-Guerrero, JA., et al. 2010. Phys Chem Chem Phys. 12: 10423-8. PMID: 20603671
  3. Characterization of natural resin shellac by reactive pyrolysis-gas chromatography in the presence of organic alkali.  |  Wang, L., et al. 1999. Anal Chem. 71: 1316-22. PMID: 21662952
  4. Simple and economic syntheses of some (Z)-7- and (Z)-9-alkenyl acetates, and of (E,Z)-7,9-dodecadien-1-yl acetate, the sex pheromone of the European grapevine moth, using aleuritic acid as a common starting material.  |  Ujváry, I., et al. 1985. J Chem Ecol. 11: 113-24. PMID: 24311103
  5. Pectin-lipid self-assembly: influence on the formation of polyhydroxy fatty acids nanoparticles.  |  Guzman-Puyol, S., et al. 2015. PLoS One. 10: e0124639. PMID: 25915490
  6. Identity of maprounic acid with aleuritolic acid. Revision of the structure of maprounic acid: X-ray crystal structure of p-bromobenzyl acetylmaprounate.  |  McPhail, AT., et al. 1989. J Nat Prod. 52: 212-6. PMID: 2723669
  7. Cellulose-polyhydroxylated fatty acid ester-based bioplastics with tuning properties: Acylation via a mixed anhydride system.  |  Heredia-Guerrero, JA., et al. 2017. Carbohydr Polym. 173: 312-320. PMID: 28732871
  8. Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells.  |  Yi, H., et al. 2018. Molecules. 23: PMID: 29865221
  9. Insoluble and Thermostable Polyhydroxyesters From a Renewable Natural Occurring Polyhydroxylated Fatty Acid.  |  Benítez, JJ., et al. 2019. Front Chem. 7: 643. PMID: 31616655
  10. Elucidating esterification reaction during deposition of cutin monomers from classical molecular dynamics simulations.  |  Bueno, OVM., et al. 2020. J Mol Model. 26: 280. PMID: 32970227
  11. Identification of Effector Metabolites Using Exometabolite Profiling of Diverse Microalgae.  |  Brisson, V., et al. 2021. mSystems. 6: e0083521. PMID: 34726483
  12. Mycobacterium tuberculosis Endonuclease VIII 2 (Nei2) forms a prereplicative BER complex with DnaN: Identification, characterization, and disruption of complex formation.  |  Lata, K., et al. 2022. Mol Microbiol. 117: 320-333. PMID: 34820919
  13. Zinc Polyaleuritate Ionomer Coatings as a Sustainable, Alternative Technology for Bisphenol A-Free Metal Packaging.  |  Morselli, D., et al. 2021. ACS Sustain Chem Eng. 9: 15484-15495. PMID: 34840919

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Aleuritic acid, 25 g

sc-252356
25 g
$245.00