Date published: 2025-11-20

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α-Solanine (CAS 20562-02-1)

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Alternate Names:
α-Solanine is also known as alpha-Solanine.
Application:
α-Solanine is a trisaccharide, consisting of glucose, galactose and rhamnose, linked to solanidine.
CAS Number:
20562-02-1
Purity:
>95%
Molecular Weight:
868.06
Molecular Formula:
C45H73NO15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Solanine is a trisaccharide,linked to solanidine. Classified as a steroidal glycoalkaloid, α-Solanine consists of glucose, galactose and rhamnose. α-Solanine is found mainly in potatoes. In pancreatic cancer cells, α-Solanine may show anti-carcinogenic potential.


α-Solanine (CAS 20562-02-1) References

  1. Acute toxicity of high doses of the glycoalkaloids, alpha-solanine and alpha-chaconine, in the Syrian Golden hamster.  |  Langkilde, S., et al. 2008. J Agric Food Chem. 56: 8753-60. PMID: 18710251
  2. The protective and therapeutic effects of alpha-solanine on mice breast cancer.  |  Mohsenikia, M., et al. 2013. Eur J Pharmacol. 718: 1-9. PMID: 24051269
  3. α-Solanine inhibits invasion of human prostate cancer cell by suppressing epithelial-mesenchymal transition and MMPs expression.  |  Shen, KH., et al. 2014. Molecules. 19: 11896-914. PMID: 25116803
  4. α-Solanine Modulates the Radiosensitivity of Esophageal Cancer Cells by Inducing MicroRNA 138 Expression.  |  Wang, Y., et al. 2016. Cell Physiol Biochem. 39: 996-1010. PMID: 27536892
  5. Inhibitory effect of α-solanine on esophageal carcinoma in vitro.  |  Wang, L., et al. 2016. Exp Ther Med. 12: 1525-1530. PMID: 27588073
  6. α-solanine enhances the chemosensitivity of esophageal cancer cells by inducing microRNA‑138 expression.  |  Wu, J., et al. 2018. Oncol Rep. 39: 1163-1172. PMID: 29328459
  7. Forensic analysis using ultra-high-performance liquid chromatography-tandem mass spectrometry with solid-phase extraction of α-solanine and α-chaconine in whole blood.  |  Nara, A., et al. 2019. Forensic Toxicol. 37: 197-206. PMID: 30636987
  8. Synergistic Effect of α-Solanine and Cisplatin Induces Apoptosis and Enhances Cell Cycle Arrest in Human Hepatocellular Carcinoma Cells.  |  El-Daly, SM., et al. 2019. Anticancer Agents Med Chem. 19: 2197-2210. PMID: 31566136
  9. α‑Solanine inhibits growth and metastatic potential of human colorectal cancer cells.  |  Yan, X., et al. 2020. Oncol Rep. 43: 1387-1396. PMID: 32323807
  10. Alpha-solanine Anti-tumor Effects in Non-small Cell Lung Cancer Through Regulating the Energy Metabolism Pathway.  |  Zou, T., et al. 2022. Recent Pat Anticancer Drug Discov. 17: 396-409. PMID: 35049438
  11. Alpha-solanine inhibits endothelial inflammation via nuclear factor kappa B signaling pathway.  |  Wang, N., et al. 2023. Adv Clin Exp Med.. PMID: 36753375
  12. Potential of Alpha-(α)-Solanine as a Natural Inhibitor of Fungus Causing Leaf Spot Disease in Strawberry.  |  Xu, N., et al. 2023. Life (Basel). 13: PMID: 36836807
  13. Bioavailability and disposition of 3H-solanine in rat and hamster.  |  Groen, K., et al. 1993. Xenobiotica. 23: 995-1005. PMID: 8291267
  14. Inhibition of human plasma and serum butyrylcholinesterase (EC 3.1.1.8) by alpha-chaconine and alpha-solanine.  |  Nigg, HN., et al. 1996. Fundam Appl Toxicol. 33: 272-81. PMID: 8921346

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Solanine, 5 mg

sc-252340
5 mg
$159.00

α-Solanine, 10 mg

sc-252340A
10 mg
$232.00

α-Solanine, 50 mg

sc-252340B
50 mg
$764.00