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6-Mercapto-1-hexanol (CAS 1633-78-9)

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Alternate Names:
6-MERCAPTOHEXAN-1-OL
CAS Number:
1633-78-9
Purity:
≥97%
Molecular Weight:
134.24
Molecular Formula:
C6H14OS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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6-Mercapto-1-hexanol (6-MH) is a versatile organic compound belonging to the alcohol family. It is a colorless and water-soluble liquid with a faint odor, characterized by a boiling point of 130°C. With its wide range of applications in biochemistry, chemistry, and pharmacology, 6-Mercapto-1-hexanol serves as useful in scientific research. It is utilized as a reagent for synthesizing various compounds, a stabilizing agent for proteins, and an investigative tool for studying biochemical processes. In laboratory experiments, 6-Mercapto-1-hexanol aids in understanding drug mechanisms, as well as elucidating the biochemical and physiological impacts of drugs on cells and organisms. Furthermore, it contributes to the exploration of protein structure and function, enzyme involvement in biochemical pathways, and the effects of drugs on the immune system. The stabilizing action of 6-Mercapto-1-hexanol on proteins is achieved through the formation of disulfide bonds between cysteine residues, enhancing protein stability. Additionally, this compound can modulate the activity of enzymes and other proteins by acting as a competitive inhibitor. Depending on the concentration and the receptor type, 6-Mercapto-1-hexanol may also act as an agonist or antagonist, providing further versatility in its applications.


6-Mercapto-1-hexanol (CAS 1633-78-9) References

  1. Direct functionalization of the hydroxyl group of the 6-mercapto-1-hexanol (MCH) ligand attached to gold nanoclusters.  |  Tan, H., et al. 2006. J Phys Chem B. 110: 21690-3. PMID: 17064127
  2. In situ scanning tunneling microscopy on the dynamic process of the replacement of coronene on au (111) by 6-mercapto-1-hexanol.  |  Wu, S. and Zhang, B. 2009. Langmuir. 25: 1385-92. PMID: 19113818
  3. Thiol-functionalization of acrylic ester monomers catalyzed by immobilized Humicola insolens cutinase.  |  Kazenwadel, C., et al. 2012. Enzyme Microb Technol. 51: 9-15. PMID: 22579385
  4. A sensitive and label-free impedimetric biosensor based on an adjunct probe.  |  Zhang, XY., et al. 2013. Anal Chim Acta. 776: 11-6. PMID: 23601275
  5. Aptamer-based Field-Effect Biosensor for Tenofovir Detection.  |  Aliakbarinodehi, N., et al. 2017. Sci Rep. 7: 44409. PMID: 28294122
  6. Organocatalyzed chemoselective ring-opening polymerizations.  |  Zhu, N., et al. 2018. Sci Rep. 8: 3734. PMID: 29487371
  7. A Microelectrode Array with Reproducible Performance Shows Loss of Consistency Following Functionalization with a Self-Assembled 6-Mercapto-1-hexanol Layer.  |  Corrigan, DK., et al. 2018. Sensors (Basel). 18: PMID: 29890722
  8. Ultratrace antibiotic sensing using aptamer/graphene-based field-effect transistors.  |  Chen, X., et al. 2019. Biosens Bioelectron. 126: 664-671. PMID: 30530212
  9. Capillary electrophoretic determination of heavy-metal ions using 11-mercaptoundecanoic acid and 6-mercapto-1-hexanol co-functionalized gold nanoparticle as colorimetric probe.  |  Bi, J., et al. 2019. J Chromatogr A. 1594: 208-215. PMID: 30772060
  10. Electrochemical impedance spectroscopy for quantization of matrix Metalloproteinase-14 based on peptides inhibiting its homodimerization and heterodimerization.  |  Ma, F., et al. 2019. Talanta. 205: 120142. PMID: 31450394
  11. Highly selective and sensitive detection of glutamate by an electrochemical aptasensor.  |  Wu, C., et al. 2022. Anal Bioanal Chem. 414: 1609-1622. PMID: 34783880
  12. Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization.  |  Imanparast, A., et al. 2022. Iran J Basic Med Sci. 25: 970-979. PMID: 36159333
  13. Electrochemical Biosensor for the Determination of Specific Antibodies against SARS-CoV-2 Spike Protein.  |  Zukauskas, S., et al. 2022. Int J Mol Sci. 24: PMID: 36614164

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

6-Mercapto-1-hexanol, 5 ml

sc-252298
5 ml
$87.00

6-Mercapto-1-hexanol, 25 ml

sc-252298A
25 ml
$293.00

Hello, I bought sc:252298 6-mercapto-1-hexanol Lot name: J2016 from your company. I couldn't reach his concentration. If you can give me the stock concentration of the chemical, I will plan my experiments accordingly. Thanks

Asked by: Evrim Durgunlu
Thank you for your question. This is a pure chemical, not a solution .
Answered by: BlakeJ
Date published: 2024-04-09

Is this item available in stock? sc-252298

Asked by: Rami
Thank you for your question. For accurate availability, shipping and pricing information regarding our chemical products, please contact Customer Service.
Answered by: Tech Service
Date published: 2019-05-14

Buongiorno, Vorrei sapere se la disponibilità di questo prodotto è immediata e quanto ci vorrebbe per ricevere il prodotto in zona Sesto fiorentino. Cordiali saluti

Asked by: DrMeddaL
Grazie per la sua domanda. I nostri prodotti possono essere spediti in tutta Italia di solito con consegna in un giorno dalla data di conferma dell´ordine. Contatti il nostro costumer care per ricevere un preventivo o semplicemente richiedere ultieriori informazioni: italia@scbt.com
Answered by: SCBT Heidelberg Support
Date published: 2018-12-21
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Rated 5 out of 5 by from ZaitounaZaitouna, AJ. et al. (PubMed 26057465) reported the synthesis and application of three new antifouling diluents for the fabrication of an E-PB HIV sensor. Among the three thiolated antifouling diluents used in this study, the methoxy-terminated diluent (C6-MEG) was synthesis and application of three new antifouling diluents for the fabrication of an E-PB HIV sensor. Among the three thiolated antifouling diluents used in this study, the methoxy-terminated diluent (C6-MEG) had a specificity factor ( 13.5) substantially higher than the sensor passivated with only 6-Mercapto-1-hexanol ( 1.5). -SCBT Publication Review
Date published: 2015-01-03
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6-Mercapto-1-hexanol is rated 5.0 out of 5 by 1.
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