Date published: 2025-10-14

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trans-Cinnamaldehyde (CAS 14371-10-9)

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Alternate Names:
trans-3-Phenyl-2-propenal
CAS Number:
14371-10-9
Purity:
≥98%
Molecular Weight:
132.16
Molecular Formula:
C9H8O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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trans-Cinnamaldehyde is a compound that delves into the synthesis of fine chemicals. It serves as a key starting material in the production of various aromatic compounds through aldol condensation reactions, which are fundamental in organic chemistry. Studies involving trans-cinnamaldehyde focus on its role in the development of new fragrance chemicals, where its cinnamon scent profile is of particular interest. It is a significant component in the study of product synthesis, as it is a basic building block for the construction of more complex molecules found in nature. Some also explore its ability to act as a precursor in the synthesis of polymers and other advanced materials that require precise functionalities introduced through organic methods.


trans-Cinnamaldehyde (CAS 14371-10-9) References

  1. Trans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice.  |  Do, J., et al. 2020. Int J Mol Sci. 21: PMID: 32599846
  2. Antifungal films from trans-cinnamaldehyde incorporated poly(lactic acid) and poly(butylene adipate-co-terephthalate) for bread packaging.  |  Srisa, A. and Harnkarnsujarit, N. 2020. Food Chem. 333: 127537. PMID: 32683265
  3. Combinatorial effects of trans-cinnamaldehyde with fluoride and chlorhexidine on Streptococcus mutans.  |  Balasubramanian, AR., et al. 2021. J Appl Microbiol. 130: 382-393. PMID: 32707601
  4. Trans-cinnamaldehyde potently kills Enterococcus faecalis biofilm cells and prevents biofilm recovery.  |  Ali, IAA., et al. 2020. Microb Pathog. 149: 104482. PMID: 32920147
  5. Trans-Cinnamaldehyde Increases Random Pattern Flap Survival Through Activation of the Nitric Oxide Pathway.  |  Luo, X., et al. 2021. Drug Des Devel Ther. 15: 679-688. PMID: 33628013
  6. Trans-Cinnamaldehyde Exhibits Synergy with Conventional Antibiotic against Methicillin-Resistant Staphylococcus aureus.  |  Wang, S., et al. 2021. Int J Mol Sci. 22: PMID: 33803167
  7. Trans-Cinnamaldehyde Attenuates Enterococcus faecalis Virulence and Inhibits Biofilm Formation.  |  Ali, IAA., et al. 2021. Antibiotics (Basel). 10: PMID: 34208134
  8. Trans-cinnamaldehyde suppresses microtubule detyrosination and alleviates cardiac hypertrophy.  |  Tian, J., et al. 2022. Eur J Pharmacol. 914: 174687. PMID: 34883072
  9. Trans-cinnamaldehyde protects against phenylephrine-induced cardiomyocyte hypertrophy through the CaMKII/ERK pathway.  |  Qian, D., et al. 2022. BMC Complement Med Ther. 22: 115. PMID: 35468773
  10. Trans-Cinnamaldehyde Eluting Porous Silicon Microparticles Mitigate Cariogenic Biofilms.  |  Jailani, A., et al. 2022. Pharmaceutics. 14: PMID: 35890323
  11. Thymol and trans-cinnamaldehyde induce apoptosis through a metacaspase-dependent mitochondrial pathway in food-spoilage yeast Zygosaccharomyces rouxii.  |  Wang, H., et al. 2022. J Food Sci. 87: 4119-4136. PMID: 35986680
  12. trans-Cinnamaldehyde-encapsulated zeolitic imidazolate framework-8 nanoparticle complex solutions to inactivate Escherichia coli O157:H7 on fresh spinach leaves.  |  Yang, X., et al. 2022. J Food Sci. 87: 4649-4664. PMID: 36045506
  13. Trans-cinnamaldehyde-Biosurfactant Complex as a Potent Agent against Enterococcus faecalis Biofilms.  |  Hu, M., et al. 2022. Pharmaceutics. 14: PMID: 36365173
  14. Derivatized chitosan-oil-in-water nanocapsules for trans-cinnamaldehyde delivery.  |  Berberolli, S., et al. 2023. Int J Biol Macromol. 240: 124464. PMID: 37062386
  15. Trans-cinnamaldehyde-related overproduction of benzoic acid and oxidative stress on Arabidopsis thaliana.  |  López-González, D., et al. 2023. Front Plant Sci. 14: 1157309. PMID: 37152151

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

trans-Cinnamaldehyde, 50 g

sc-251282
50 g
$26.00

trans-Cinnamaldehyde, 500 g

sc-251282A
500 g
$53.00