Date published: 2025-10-16

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Propiconazole (CAS 60207-90-1)

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Alternate Names:
Proconazole; Propiconazol; Propyconazol
Application:
Propiconazole is a systemic foliar and agricultural fungicide
CAS Number:
60207-90-1
Molecular Weight:
342.22
Molecular Formula:
C15H17Cl2N3O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propiconazole is a potent triazole fungicide that disrupts fungal cell membranes by inhibiting the conversion of lanosterol to ergosterol. It effectively inhibits the growth of various fungi, such as T. deformans, R. stolonifer, A. niger, M. fructigena, S. nodorum, T. harzanium, R. solani, and S. rolfsii, at concentrations ranging from 0.1 to 5 ppm. This broad-spectrum fungicide has been widely used in agriculture for controlling fungal infections.n addition to its antifungal properties, propiconazole has been found to have specific effects on biological systems. It inhibits S. cerevisiae but does not affect rat liver microsomal cytochrome P450. Propiconazole is a systemic fungicide that works by inhibiting ergosterol biosynthesis. It is a cyclic ketal derived from the condensation of 1-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone with pentane-1,2-diol. It is a yellowish, odorless liquid that is non-corrosive.


Propiconazole (CAS 60207-90-1) References

  1. Characterization of propiconazole field-resistant isolates of Ustilaginoidea virens.  |  Zhou, Y., et al. 2019. Pestic Biochem Physiol. 153: 144-151. PMID: 30744888
  2. Effect of Propiconazole on the Lipid Metabolism of Zebrafish Embryos (Danio rerio).  |  Teng, M., et al. 2019. J Agric Food Chem. 67: 4623-4631. PMID: 30950260
  3. Propiconazole induces abnormal behavior and oxidative stress in zebrafish.  |  Valadas, J., et al. 2019. Environ Sci Pollut Res Int. 26: 27808-27815. PMID: 31342352
  4. Life cycle exposure to propiconazole reduces fecundity by disrupting the steroidogenic pathway and altering DNA methylation in zebrafish (Danio rerio).  |  Teng, M., et al. 2020. Environ Int. 135: 105384. PMID: 31862640
  5. Peer review of the pesticide risk assessment of the active substance propiconazole.  |  , ., et al. 2017. EFSA J. 15: e04887. PMID: 32625552
  6. Wheat phyllosphere yeasts degrade propiconazole.  |  Kucharska, K., et al. 2020. BMC Microbiol. 20: 242. PMID: 32758148
  7. Baseline sensitivity and fungicidal action of propiconazole against Penicillium digitatum.  |  Zhang, J., et al. 2021. Pestic Biochem Physiol. 172: 104752. PMID: 33518045
  8. Four Propiconazole Stereoisomers: Stereoselective Bioactivity, Separation via Liquid Chromatography-Tandem Mass Spectrometry, and Dissipation in Banana Leaves.  |  Tang, S., et al. 2022. J Agric Food Chem. 70: 877-886. PMID: 35029107
  9. Effect of propiconazole on plastic film microplastic degradation: Focusing on the change in microplastic morphology and heavy metal distribution.  |  Lin, Y., et al. 2022. Sci Total Environ. 822: 153609. PMID: 35121034
  10. Propiconazole degradation and its toxicity removal during UV/H2O2 and UV photolysis processes.  |  Hong, AJ., et al. 2022. Chemosphere. 302: 134876. PMID: 35551935
  11. Parental exposure to propiconazole at environmentally relevant concentrations induces thyroid and metabolism disruption in zebrafish (Danio rerio) offspring: An in vivo, in silico and in vitro study.  |  Teng, M., et al. 2022. Ecotoxicol Environ Saf. 242: 113865. PMID: 35870346
  12. Effect of propiconazole on neutrophil extracellular traps formation: Assessing the role of autophagy.  |  Ma, Y., et al. 2022. Food Chem Toxicol. 168: 113354. PMID: 35952824
  13. Environmental Hormone Effects and Bioaccumulation of Propiconazole and Difenoconazole in Procypris merus.  |  Chen, L., et al. 2022. Bull Environ Contam Toxicol. 109: 823-830. PMID: 36074130

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propiconazole, 250 mg

sc-250786
250 mg
$120.00

Propiconazole, 1 g

sc-250786A
1 g
$400.00