Date published: 2025-12-5

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Cadaverine (CAS 462-94-2)

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Alternate Names:
Pentamethylenediamine
Application:
Cadaverine is a biogenic amine
CAS Number:
462-94-2
Purity:
≥97%
Molecular Weight:
102.18
Molecular Formula:
C5H14N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cadaverine, an organic compound generated during protein breakdown in the putrefaction process, emits a repugnant odor. It is classified as a diamine due to its possession of two amino groups and is found in decaying animal tissue and putrefying fish. This compound finds application in various industries and scientific endeavors, particularly in the laboratory where it aids in the study of the biochemical effects of putrefaction and related processes. The believed mode of action of cadaverine involves the inhibition of specific enzymes responsible for protein breakdown. Notably, cadaverine is thought to hinder the activity of proteases, enzymes for breaking down proteins into smaller molecules. Furthermore, it is believed to impede the function of aminopeptidases, enzymes responsible for breaking down peptides into amino acids.


Cadaverine (CAS 462-94-2) References

  1. Metabolic engineering of Corynebacterium glutamicum for cadaverine fermentation.  |  Mimitsuka, T., et al. 2007. Biosci Biotechnol Biochem. 71: 2130-5. PMID: 17895539
  2. Cadaverine: a lysine catabolite involved in plant growth and development.  |  Tomar, PC., et al. 2013. Plant Signal Behav. 8: doi: 10.4161/psb.25850. PMID: 23887488
  3. High-affinity olfactory receptor for the death-associated odor cadaverine.  |  Hussain, A., et al. 2013. Proc Natl Acad Sci U S A. 110: 19579-84. PMID: 24218586
  4. Modification of cadaverine content by NO in salt-stressed maize.  |  Simon-Sarkadi, L., et al. 2014. Plant Signal Behav. 9: e27598. PMID: 24398894
  5. Cadaverine Production by Using Cross-Linked Enzyme Aggregate of Escherichia coli Lysine Decarboxylase.  |  Park, SH., et al. 2017. J Microbiol Biotechnol. 27: 289-296. PMID: 27780956
  6. The biogenic amines putrescine and cadaverine show in vitro cytotoxicity at concentrations that can be found in foods.  |  Del Rio, B., et al. 2019. Sci Rep. 9: 120. PMID: 30644398
  7. Minicircle DNA purification: Performance of chromatographic monoliths bearing lysine and cadaverine ligands.  |  Almeida, AM., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1118-1119: 7-16. PMID: 31005775
  8. Analytical possibilities of Putrescine and Cadaverine enzymatic colorimetric determination in tuna based on diamine oxidase: A critical study of the use of ABTS.  |  Navarro, J., et al. 2020. Talanta. 208: 120392. PMID: 31816694
  9. High-efficiency and low-cost production of cadaverine from a permeabilized-cell bioconversion by a Lysine-induced engineered Escherichia coli.  |  Rui, J., et al. 2020. Bioresour Technol. 302: 122844. PMID: 32006927
  10. Silver Nanoparticles for a Colorimetric Determination of Putrescine and Cadaverine in Biological Samples.  |  Ghoto, SA. and Khuhawar, MY. 2021. Anal Sci. 37: 267-274. PMID: 32779576
  11. Fabrication of bio-based polyamide 56 and antibacterial nanofiber membrane from cadaverine.  |  Xue, C., et al. 2021. Chemosphere. 266: 128967. PMID: 33218735
  12. Improvement of cadaverine production in whole cell system with baker's yeast for cofactor regeneration.  |  Han, YH., et al. 2021. Bioprocess Biosyst Eng. 44: 891-899. PMID: 33486578
  13. Electrified liquid-liquid interface as an electrochemical tool for the sensing of putrescine and cadaverine.  |  Sudalaimani, S., et al. 2021. Analyst. 146: 3208-3215. PMID: 33999050
  14. Engineered Halomonas spp. for production of l-Lysine and cadaverine.  |  Zhao, C., et al. 2022. Bioresour Technol. 349: 126865. PMID: 35183730
  15. A possible role of cadaverine in the biosynthesis of polyamines in the Japanese newt testis.  |  Matsuzaki, S., et al. 1981. Endocrinol Jpn. 28: 305-12. PMID: 6796394

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cadaverine, 10 ml

sc-239454
10 ml
$212.00