Date published: 2025-11-20

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Bis(2-hydroxyphenyl)methane (CAS 2467-02-9)

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Alternate Names:
2,2′-Methylenediphenol
CAS Number:
2467-02-9
Molecular Weight:
200.23
Molecular Formula:
C13H12O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Bis(2-hydroxyphenyl)methane, also known as BPA, is an organic compound with the ability to bind to estrogen receptors. Within the scientific field, Bis(2-hydroxyphenyl)methane finds broad utility. Its employment as a monomer enables the creation of polycarbonates, epoxy resins, and other polymers. Further, it serves as a raw material for synthesizing flame retardants, and adhesives. Bis(2-hydroxyphenyl)methane, facilitates investigations on the impacts of environmental contaminants on health and elucidating the effects of endocrine disruptors on organismal development.Notably, Bis(2-hydroxyphenyl)methane acts as an endocrine disruptor, exerting interference with the normal functioning of hormones.


Bis(2-hydroxyphenyl)methane (CAS 2467-02-9) References

  1. Vibrational spectra and conformational isomerism of calixarene building blocks: 2-benzylphenol.  |  Katsyuba, S., et al. 2003. Org Biomol Chem. 1: 714-9. PMID: 12929459
  2. Synthesis and antimicrobial activities of halogenated bis(hydroxyphenyl)methanes.  |  Oh, KB., et al. 2009. Bioorg Med Chem Lett. 19: 945-8. PMID: 19097894
  3. Conformational effects on excitonic interactions in a prototypical H-bonded bichromophore: bis(2-hydroxyphenyl)methane.  |  Pillsbury, NR., et al. 2009. J Phys Chem A. 113: 5000-12. PMID: 19348452
  4. Conformational isomerization and collisional cooling dynamics of bis(2-hydroxyphenyl)methane.  |  Pillsbury, NR., et al. 2009. J Phys Chem A. 113: 5013-21. PMID: 19348453
  5. Calixarene building block bis(2-hydroxyphenyl)methane (2HDPM) and hydrogen-bonded 2HDPM-H₂O complex in electronic excited state.  |  Wang, S., et al. 2013. J Mol Model. 19: 1913-8. PMID: 23334370
  6. The Adsorption of Multinuclear Phenolic Compounds on Activated Carbon  |  T.R. Dargaville, F.N. Guerzoni, M.G. Looney, D.H. Solomon 1. 1996. Journal of Colloid and Interface Science. 182: 17-25.
  7. Thermal degradation of halogen-free flame retardant epoxides and polycarbonate in air  |  Luz Becker 1, D. Lenoir, G. Matuschek, A. Kettrup 2. 2001. Journal of Analytical and Applied Pyrolysis. 60: 55-67.
  8. Indium(III) chloride catalyzed one step synthesis of some new dibenzo(d,f)(1,3)dioxepines and 12H-dibenzo(d,g)(1,3)dioxocin derivatives  |  Graziella Tocco 1, Michela Begala, Giovanna Delogu, Carmen Picciau, Gianni Podda. 2004. Tetrahedron Letters. 45: 6909-6913.
  9. The Anti-Leishmanial Effects of Compounds Derived from the Fungus Geosmithia langdonii on Visceral Leishmaniasis  |  Nicole Atencio, Kenny Milller, Austin Cheney, B. Andre Benally. 2020. The FASEB Journal. 34: 1-1.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Bis(2-hydroxyphenyl)methane, 1 g

sc-239354
1 g
$107.00