Bacitracin zinc salt (CAS 1405-89-6)
QUICK LINKS
Bacitracin zinc salt functions as an inhibitor of bacterial cell wall synthesis. It achieves this by interfering with the dephosphorylation of the lipid carrier, which is necessary for the transport of peptidoglycan precursors across the cell membrane. This disruption ultimately leads to the inhibition of peptidoglycan synthesis, resulting in weakened bacterial cell walls and subsequent cell lysis. Bacitracin zinc salt′s mechanism of action involves binding to the cell membrane and interfering with the dephosphorylation process, thereby disrupting the synthesis of peptidoglycan. This interference at the molecular level ultimately leads to the destabilization of bacterial cell walls, which may be useful for studying bacterial cell wall synthesis and potential applications in experimental applications.
Bacitracin zinc salt (CAS 1405-89-6) References
- Analysis of bacitracin by micellar electrokinetic capillary chromatography with mixed micelle in acidic solution. | Kang, JW., et al. 2001. Electrophoresis. 22: 1356-62. PMID: 11379958
- Regulation of the Bacillus subtilis bcrC bacitracin resistance gene by two extracytoplasmic function sigma factors. | Cao, M. and Helmann, JD. 2002. J Bacteriol. 184: 6123-9. PMID: 12399481
- Clonal strains of Pseudomonas aeruginosa in paediatric and adult cystic fibrosis units. | O'Carroll, MR., et al. 2004. Eur Respir J. 24: 101-6. PMID: 15293611
- Regulatory overlap and functional redundancy among Bacillus subtilis extracytoplasmic function sigma factors. | Mascher, T., et al. 2007. J Bacteriol. 189: 6919-27. PMID: 17675383
- Bioluminescence imaging of hematopoietic stem cell repopulation in murine models. | Lin, Y., et al. 2008. Methods Mol Biol. 430: 295-306. PMID: 18370307
- Hyperactivity of the dopaminergic system in NTS1 and NTS2 null mice. | Liang, Y., et al. 2010. Neuropharmacology. 58: 1199-205. PMID: 20211191
- Tripropeptin C blocks the lipid cycle of cell wall biosynthesis by complex formation with undecaprenyl pyrophosphate. | Hashizume, H., et al. 2011. Antimicrob Agents Chemother. 55: 3821-8. PMID: 21628543
- Accumulation of heptaprenyl diphosphate sensitizes Bacillus subtilis to bacitracin: implications for the mechanism of resistance mediated by the BceAB transporter. | Kingston, AW., et al. 2014. Mol Microbiol. 93: 37-49. PMID: 24806199
- Gut microbiota: Firmicutes and Bacteroidetes involved in insulin resistance by mediating levels of glucagon-like peptide 1. | Greenhill, C. 2015. Nat Rev Endocrinol. 11: 254. PMID: 25781856
- Selective ciprofloxacin antibiotic detection by fluorescent siderophore pyoverdin. | Pawar, MK., et al. 2016. Biosens Bioelectron. 81: 274-279. PMID: 26971273
- Antibacterial Chitosan Nanofiber Thin Films with Bacitracin Zinc Salt. | Kumamoto, K., et al. 2021. Polymers (Basel). 13: PMID: 33808445
- Solubility of antibiotics used in animal feeds in selected solvents. | Salvatore, MJ. and Katz, SE. 1993. J AOAC Int. 76: 952-6. PMID: 8241823
- High Performance Liquid Chromatographic Separation of Bacitracin Methylenedisalicylate | Milenko Sokolic and & Viljem Pavli. 1991 -. Journal of Liquid Chromatography. Volume 14, Issue 10: Pages 1977-1981.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Bacitracin zinc salt, 1 g | sc-239267 | 1 g | $20.00 |