Date published: 2025-11-20

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α-Ketoglutaric acid disodium salt dihydrate (CAS 305-72-6)

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Alternate Names:
2-Oxoglutaric acid disodium salt; Sodium α-ketoglutarate dibasic
CAS Number:
305-72-6
Purity:
≥98%
Molecular Weight:
226.09
Molecular Formula:
C5H4Na2O52H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Ketoglutaric acid disodium salt dihydrate is a naturally occurring compound found in many organisms, including humans, and is used in many biochemical and physiological processes. It is an important component of the Krebs cycle, which is a metabolic pathway that helps to generate energy in cells. It is also used in the synthesis of amino acids and other important molecules, and is involved in the regulation of gene expression. In the Krebs cycle, α-Ketoglutaric acid disodium salt dihydrate is converted to succinyl-CoA, which is then used to produce energy. α-Ketoglutaric acid disodium salt dihydrate is also involved in the regulation of gene expression. It is a coenzyme that helps to activate transcription factors, which are proteins that bind to DNA and regulate gene expression.


α-Ketoglutaric acid disodium salt dihydrate (CAS 305-72-6) References

  1. A new chromatographic response function for use in size-exclusion chromatography optimization strategies: Application to complex organic mixtures.  |  Duarte, RM. and Duarte, AC. 2010. J Chromatogr A. 1217: 7556-63. PMID: 21030026
  2. Identification of metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii.  |  Miquel, S., et al. 2015. mBio. 6: PMID: 25900655
  3. An analytical quality by design (aQbD) approach for a L-asparaginase activity method.  |  Yao, H., et al. 2016. J Pharm Biomed Anal. 117: 232-9. PMID: 26378979
  4. Aminotransferase and glutamate dehydrogenase activities in lactobacilli and streptococci.  |  Peralta, GH., et al. 2016. Braz J Microbiol. 47: 741-8. PMID: 27266631
  5. Unbiased biocatalytic solar-to-chemical conversion by FeOOH/BiVO4/perovskite tandem structure.  |  Lee, YW., et al. 2018. Nat Commun. 9: 4208. PMID: 30310064
  6. Tricarboxylic Acid (TCA) Cycle Enzymes and Intermediates Modulate Intracellular Cyclic di-GMP Levels and the Production of Plant Cell Wall-Degrading Enzymes in Soft Rot Pathogen Dickeya dadantii.  |  Yuan, X., et al. 2020. Mol Plant Microbe Interact. 33: 296-307. PMID: 31851880
  7. Efficient Chemoenzymatic Synthesis of (2S,3R)-3-Hydroxy-3-Methylproline, a Key Fragment in Polyoxypeptin A and FR225659.  |  Zhang, X. and Renata, H. 2019. Tetrahedron. 75: 3253-3257. PMID: 31885405
  8. An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase.  |  Raiymbek, G., et al. 2020. Elife. 9: PMID: 32195666
  9. Combining tRNA sequencing methods to characterize plant tRNA expression and post-transcriptional modification.  |  Warren, JM., et al. 2021. RNA Biol. 18: 64-78. PMID: 32715941
  10. Detection of TET-Oxidized 5-Methylcytosine Bases by Capillary Gel Electrophoresis.  |  Vaisvila, R., et al. 2021. Methods Mol Biol. 2198: 137-144. PMID: 32822028
  11. A plausible metal-free ancestral analogue of the Krebs cycle composed entirely of α-ketoacids.  |  Stubbs, RT., et al. 2020. Nat Chem. 12: 1016-1022. PMID: 33046840
  12. Hopeful monsters: unintended sequencing of famously malformed mite mitochondrial tRNAs reveals widespread expression and processing of sense-antisense pairs.  |  Warren, JM. and Sloan, DB. 2021. NAR Genom Bioinform. 3: lqaa111. PMID: 33575653
  13. CRISPR screens in physiologic medium reveal conditionally essential genes in human cells.  |  Rossiter, NJ., et al. 2021. Cell Metab. 33: 1248-1263.e9. PMID: 33651980
  14. Rapid Shifts in Mitochondrial tRNA Import in a Plant Lineage with Extensive Mitochondrial tRNA Gene Loss.  |  Warren, JM., et al. 2021. Mol Biol Evol. 38: 5735-5751. PMID: 34436590
  15. Gadolinium-Based Paramagnetic Relaxation Enhancement Agent Enhances Sensitivity for NUS Multidimensional NMR-Based Metabolomics.  |  Honrao, C., et al. 2021. Molecules. 26: PMID: 34500549

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Ketoglutaric acid disodium salt dihydrate, 25 g

sc-239159
25 g
$46.00

α-Ketoglutaric acid disodium salt dihydrate, 100 g

sc-239159A
100 g
$153.00

α-Ketoglutaric acid disodium salt dihydrate, 250 g

sc-239159B
250 g
$388.00