Date published: 2025-11-20

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2,5-Dimethoxybenzyl alcohol (CAS 33524-31-1)

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CAS Number:
33524-31-1
Molecular Weight:
168.19
Molecular Formula:
C9H12O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2,5-Dimethoxybenzyl alcohol is used as a self-indicating standard for assessing organolithium reagents. This compound has various applications within scientific research, functioning as a reagent in organic synthesis, a solvent for diverse reactions, and a substrate for enzyme assays. Moreover, it stands as a model compound in the studies of enzyme inhibition and functioning as a probe for the analysis of protein-protein interactions.


2,5-Dimethoxybenzyl alcohol (CAS 33524-31-1) References

  1. Structural effects on the OH-promoted fragmentation of methoxy-substituted 1-arylalkanol radical cations in aqueous solution: the role of oxygen acidity.  |  Baciocchi, E., et al. 2001. Chemistry. 7: 1408-16. PMID: 11330893
  2. Use of multiplex reverse transcription-PCR to study the expression of a laccase gene family in a basidiomycetous fungus.  |  González, T., et al. 2003. Appl Environ Microbiol. 69: 7083-90. PMID: 14660352
  3. Design, synthesis and biological evaluation of novel riccardiphenol analogs.  |  Kumar, SK., et al. 2005. Bioorg Med Chem. 13: 2873-80. PMID: 15781397
  4. Synthesis of new phytogrowth-inhibitory substituted aryl-p-benzoquinones.  |  de Almeida Barbosa, LC., et al. 2006. Chem Biodivers. 3: 553-67. PMID: 17193291
  5. Catalytic hypervalent iodine oxidation of p-dialkoxybenzenes to p-quinones using 4-iodophenoxyacetic acid and Oxone.  |  Yakura, T., et al. 2008. Chem Pharm Bull (Tokyo). 56: 1632-4. PMID: 18981622
  6. Mechanistic borderline of one-step hydrogen atom transfer versus stepwise Sc(3+)-coupled electron transfer from benzyl alcohol derivatives to a non-heme iron(IV)-oxo complex.  |  Morimoto, Y., et al. 2012. Inorg Chem. 51: 10025-36. PMID: 22954389
  7. Detection of glucose via enzyme-coupling reaction based on a DT-diaphorase fluorescence probe.  |  Gao, X., et al. 2014. Talanta. 120: 456-61. PMID: 24468396
  8. Acid-Triggered Colorimetric Hydrophobic Benzyl Alcohols for Soluble Tag-Assisted Liquid-Phase Synthesis.  |  Okada, Y., et al. 2015. Org Lett. 17: 4264-7. PMID: 26274781
  9. Chemical Composition, Antioxidant and Cytotoxic Activities of Essential Oil of the Inflorescence of Anacamptis coriophora subsp. fragrans (Orchidaceae) from Tunisia.  |  El Mokni, R., et al. 2016. Nat Prod Commun. 11: 857-60. PMID: 27534135
  10. Photoinitiating Systems Based on Anthraquinone Derivatives: Synthesis of Antifouling and Biocide Coatings.  |  Tomane, S., et al. 2017. Chempluschem. 82: 1298-1307. PMID: 31957991
  11. Traditional, Therapeutic Uses and Phytochemistry of Terrestrial European Orchids and Implications for Conservation.  |  Bazzicalupo, M., et al. 2023. Plants (Basel). 12: PMID: 36678970
  12. 2, 5-Dimethoxybenzyl alcohol: a convenient self-indicating standard for the determination of organolithium reagents  |  Winkle, M. R., Lansinger, J. M., & Ronald, R. C. 1980. Journal of the Chemical Society, Chemical Communications,. (3): 87-88.
  13. A formal synthesis of optically active clavicipitic acids, unusual azepinoindole-type ergot alkaloids  |  Shinohara, H., Fukuda, T., & Iwao, M. 1999. Tetrahedron. 55(36): 10989-11000.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2,5-Dimethoxybenzyl alcohol, 10 g

sc-238381
10 g
$87.00