Molecular structure of 2-Hydroxyethyl methacrylate, CAS Number: 868-77-9
2-Hydroxyethyl methacrylate (CAS 868-77-9)
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Alternate Names:
1,2-Ethanediol mono(2-methylpropenoate); Glycol methacrylate; HEMA
Application:
2-Hydroxyethyl methacrylate is wide applications for drug delivery
CAS Number:
868-77-9
Purity:
97%
Molecular Weight:
130.14
Molecular Formula:
C6H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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2-Hydroxyethyl methacrylate, also known as HEMA, was the first monomer to be used to synthesize hydrogels for biomedical applications. The water swelling properties of 2-Hydroxyethyl methacrylate are enhanced by copolymerization with more hydrophilic monomers. It is used in the synthesis of biologically functional poly (2-hydroxyethyl methacrylate) (PHEMA) coplymers. Also, it is used to prepare light responsive membranes of PHEMA, HEMA/ acrylamide based specific drug release hydrogel, and water soluble 2-Hydroxyethyl methacrylate/methacrylic acid hydrogel for drug delivery. Effects of 2-Hydroxyethyl methacrylate on the migration of dental pulp stem cells (in vitro) may be studied.
2-Hydroxyethyl methacrylate (CAS 868-77-9) References
- 2-hydroxyethyl methacrylate as an inhibitor of matrix metalloproteinase-2. | Carvalho, RV., et al. 2009. Eur J Oral Sci. 117: 64-7. PMID: 19196320
- 2-Hydroxyethyl methacrylate inflammatory effects in human gingival fibroblasts. | Di Nisio, C., et al. 2013. Int Endod J. 46: 466-76. PMID: 23137186
- Antioxidant Properties of 2-Hydroxyethyl Methacrylate-Based Copolymers with Incorporated Sterically Hindered Amine. | Poláková, L., et al. 2015. Biomacromolecules. 16: 2726-34. PMID: 26258477
- Poly(glycidyl methacrylate-co-2-hydroxyethyl methacrylate) Brushes as Peptide/Protein Microarray Substrate for Improving Protein Binding and Functionality. | Lei, Z., et al. 2016. ACS Appl Mater Interfaces. 8: 10174-82. PMID: 27049528
- The effects of 2-hydroxyethyl methacrylate on matrix metalloproteinases 2 and 9 in human pulp cells and odontoblast-like cells in vitro. | Sun, S., et al. 2018. Int Endod J. 51 Suppl 2: e157-e166. PMID: 28667765
- Light-Activated, Bioadhesive, Poly(2-hydroxyethyl methacrylate) Brush Coatings. | Wang, J., et al. 2020. Biomacromolecules. 21: 240-249. PMID: 31596075
- Mechanically adaptive implants fabricated with poly(2-hydroxyethyl methacrylate)-based negative photoresists. | Monney, B., et al. 2020. J Mater Chem B. 8: 6357-6365. PMID: 32555874
- Insight into carbohydrate polymers (chitosan and 2- hydroxyethyl methacrylate/methyl methacrylate) intercalated bentonite-based nanocomposites as multifunctional and environmental adsorbents for methyl parathion pesticide. | Abukhadra, MR., et al. 2021. Int J Biol Macromol. 167: 335-344. PMID: 33278429
- Influence of 2-hydroxyethyl methacrylate (HEMA) exposure on angiogenic differentiation of dental pulp stem cells (DPSCs). | Jochums, A., et al. 2021. Dent Mater. 37: 534-546. PMID: 33579530
- Allergic contact dermatitis caused by 2-hydroxyethyl methacrylate and ethyl cyanoacrylate contained in cosmetic glues among hairdressers and beauticians who perform nail treatments and eyelash extension as well as hair extension applications: A systematic review. | Symanzik, C., et al. 2022. Contact Dermatitis. 86: 480-492. PMID: 35088905
- Antimicrobial properties of a new polymeric material based on poly(2-hydroxyethyl methacrylate). | Chornopyshchuk, R., et al. 2022. Acta Biomed. 93: e2022012. PMID: 35315392
- Evaluation of 2-hydroxyethyl methacrylate as comonomer in the preparation of water-compatible molecularly imprinted polymers for triazinic herbicides. | Díaz-Álvarez, M., et al. 2022. J Sep Sci. 45: 2356-2365. PMID: 35478484
- 2-hydroxyethyl methacrylate-derived reactive oxygen species stimulate ATP release via TRPA1 in human dental pulp cells. | Orimoto, A., et al. 2022. Sci Rep. 12: 12343. PMID: 35853988
- Room-Temperature Self-Healable Blends of Waterborne Polyurethanes with 2-Hydroxyethyl Methacrylate-Based Polymers. | Tzoumani, I., et al. 2023. Int J Mol Sci. 24: PMID: 36768898
- Allergic contact dermatitis from 2-hydroxyethyl methacrylate in an adhesive on an electrosurgical earthing plate. | Kanerva, L. and Alanko, K. 1998. Eur J Dermatol. 8: 521-4. PMID: 9854170
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2-Hydroxyethyl methacrylate, 5 g | sc-238082 | 5 g | $20.00 | |||
2-Hydroxyethyl methacrylate, 500 g | sc-238082A | 500 g | $38.00 |