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2-Benzoylpyridine (CAS 91-02-1)

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Alternate Names:
Phenyl 2-pyridyl ketone
CAS Number:
91-02-1
Molecular Weight:
183.21
Molecular Formula:
C12H9NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Benzoylpyridine (2-BP) is an aromatic heterocyclic compound, belonging to the pyridine class, with a distinctive chemical structure and properties. Found naturally in essential oils like lavender and rosemary, it serves as a key ingredient in the synthesis of various agrochemicals and other industrial compounds. The versatility of 2-Benzoylpyridine allows for its wide range of applications. In recent years, extensive research has been conducted on 2-Benzoylpyridine′s potential uses in both medical and agricultural fields. For agriculture, it has shown promise as an effective herbicide, insecticide, and fungicide. Moreover, 2-Benzoylpyridine has been explored as a catalyst to facilitate the synthesis of diverse compounds. While the exact mechanism of action is not fully understood, scientists believe that 2-Benzoylpyridine interacts with certain proteins in the body, initiating a series of biochemical reactions. The binding of the compound to proteins in the cell membrane triggers the release of enzymes and hormones, ultimately resulting in the desired effects, such as inhibiting cell growth or stimulating specific biochemical pathways. 2-Benzoylpyridine, with its intriguing properties and applications, continues to be a subject of significant interest in various fields, offering potential breakthroughs in agriculture and industrial chemistry.


2-Benzoylpyridine (CAS 91-02-1) References

  1. Concentration-dependent surface-enhanced Raman scattering of 2-benzoylpyridine adsorbed on colloidal silver particles.  |  Chowdhury, J. and Ghosh, M. 2004. J Colloid Interface Sci. 277: 121-7. PMID: 15276048
  2. Ruthenium(II) complexes containing 2-pyridineformamide- and 2-benzoylpyridine-derived thiosemicarbazones and PPh3: NMR and electrochemical studies of cis-trans-isomerization.  |  Graminha, AE., et al. 2008. Spectrochim Acta A Mol Biomol Spectrosc. 69: 1277-82. PMID: 17822950
  3. Application of the deford and hume method modified for quasi-reversible and irreversible processes to the chelates of Bi(III) with azomethine derivatives of 2-benzoylpyridine.  |  Gomez-Nieto, MA., et al. 1984. Talanta. 31: 379-85. PMID: 18963615
  4. 2-Benzoylpyridine-N(4)-tolyl thiosemicarbazones and their palladium(II) complexes: cytotoxicity against leukemia cells.  |  Ferraz, KS., et al. 2009. Bioorg Med Chem. 17: 7138-44. PMID: 19773176
  5. Reaction of β-diketiminate tin(II) dimethylamide LSnNMe₂ [L = HC(CMeNAr)₂; Ar = 2,6-iPr₂C₆H₃] with ketones and alkynes.  |  Jana, A., et al. 2010. Dalton Trans. 39: 4647-50. PMID: 20401416
  6. Unravelling the reaction mechanism for the fast photocyclisation of 2-benzoylpyridine in aqueous solvent by time-resolved spectroscopy and density functional theory calculations.  |  Du, Y., et al. 2010. Chemistry. 16: 6961-72. PMID: 20437422
  7. 2-Acetylpyridine- and 2-benzoylpyridine-derived hydrazones and their gallium(III) complexes are highly cytotoxic to glioma cells.  |  Despaigne, AA., et al. 2012. Eur J Med Chem. 50: 163-72. PMID: 22357115
  8. Excited electronic states and Raman spectra of 2-benzoylpyridine.  |  Datta, S., et al. 2013. Appl Spectrosc. 67: 1447-62. PMID: 24359660
  9. Interesting copper(ii)-assisted transformations of 2-acetylpyridine and 2-benzoylpyridine.  |  Kitos, AA., et al. 2016. Dalton Trans. 45: 1063-77. PMID: 26659333
  10. Rhodium (II) complex with 2-benzoylpyridine, a novel potential chemotherapeutic drug, induces cell cycle arrest and apoptosis in HepG2 cells.  |  Wang, X., et al. 2017. Biometals. 30: 903-915. PMID: 28993927
  11. 2-Benzoylpyridine Ligand Complexation with Gold Critical for Propargyl Ester-Based Protein Labeling.  |  Lin, Y., et al. 2018. Chemistry. 24: 10595-10600. PMID: 29791049
  12. Two azido-bridged homospin Fe(ii)/Co(ii) coordination polymers featuring single-chain magnet behavior.  |  Yang, J., et al. 2020. Dalton Trans. 49: 4805-4810. PMID: 32211706
  13. Indium(III)/2-benzoylpyridine chemistry: interesting indium(III) bromide-assisted transformations of the ligand.  |  Stamou, C., et al. 2022. Dalton Trans. 51: 15771-15782. PMID: 36178466

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Benzoylpyridine, 25 g

sc-237918
25 g
$20.00