1,6-Hexanediol (CAS 629-11-8)
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1,6-Hexanediol is an organic compound that is frequently studied for its applications in polymer chemistry. It is a key monomer in the production of polyurethanes and polyester resins, where its diol functionality allows it to react with diisocyanates and diacid chlorides, respectively. The compound′s linear structure and symmetrical nature are of interest in research that aims to develop polymers with specific mechanical and thermal properties. In addition to its use as a monomer, 1,6-Hexanediol is investigated for its role as a chain extender in polymer systems, which can affect the molecular weight and polydispersity of the resulting materials. Research involving 1,6-Hexanediol is also focused on its potential to form polyesters that are biodegradable, as its aliphatic nature may lend itself to enzymatic degradation, which is important for creating more sustainable materials.
1,6-Hexanediol (CAS 629-11-8) References
- Evaluation of determination of lactate dehydrogenase isoenzyme 1 by chemical inhibition with perchlorate or with 1,6-hexanediol. | Paz, JM., et al. 1990. Clin Chem. 36: 355-8. PMID: 2154344
- Theoretical calculation of the OH vibrational overtone spectra of 1,5-pentanediol and 1,6-hexanediol. | Chen, HY., et al. 2011. J Phys Chem A. 115: 14315-24. PMID: 22066681
- Direct synthesis of 1,6-hexanediol from HMF over a heterogeneous Pd/ZrP catalyst using formic acid as hydrogen source. | Tuteja, J., et al. 2014. ChemSusChem. 7: 96-100. PMID: 24259303
- Radiopaque, iodine functionalized, phenylalanine-based poly(ester urea)s. | Li, S., et al. 2015. Biomacromolecules. 16: 615-24. PMID: 25575022
- Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation. | Yamazaki, T., et al. 2018. Mol Cell. 70: 1038-1053.e7. PMID: 29932899
- Unique Lewis and Bronsted acidic sites texture in the selective production of tetrahydropyran and oxepanefrom1,5-pentanediol and 1,6-hexanediol over sustainable red brick clay catalyst. | Madduluri, VR., et al. 2019. Heliyon. 5: e01212. PMID: 30809597
- 1,6-hexanediol rapidly immobilizes and condenses chromatin in living human cells. | Itoh, Y., et al. 2021. Life Sci Alliance. 4: PMID: 33536240
- Simultaneous production of 1,6-hexanediol, furfural, and high-purity lignin from white birch: Process integration and techno-economic evaluation. | Kim, H., et al. 2021. Bioresour Technol. 331: 125009. PMID: 33780837
- 1,6-Hexanediol, commonly used to dissolve liquid-liquid phase separated condensates, directly impairs kinase and phosphatase activities. | Düster, R., et al. 2021. J Biol Chem. 296: 100260. PMID: 33814344
- RNA-induced liquid phase separation of SARS-CoV-2 nucleocapsid protein facilitates NF-κB hyper-activation and inflammation. | Wu, Y., et al. 2021. Signal Transduct Target Ther. 6: 167. PMID: 33895773
- Time-dependent effect of 1,6-hexanediol on biomolecular condensates and 3D chromatin organization. | Liu, X., et al. 2021. Genome Biol. 22: 230. PMID: 34404453
- Targeting liquid-liquid phase separation in pancreatic cancer. | Ming, Y., et al. 2019. Transl Cancer Res. 8: 96-103. PMID: 35116738
- Selective determination of lactate dehydrogenase isoenzyme 1 in serum after inhibition by 1,6-hexanediol. | Tanishima, K., et al. 1987. J Clin Chem Clin Biochem. 25: 729-32. PMID: 3694131
- 1,6-Hexanediol regulates angiogenesis via suppression of cyclin A1-mediated endothelial function. | Jiang, Y., et al. 2023. BMC Biol. 21: 75. PMID: 37024934
- Impact of 1,6-Hexanediol on Schizosaccharomyces pombe Genome Stability. | Jones, CE. and Forsburg, SL. 2023. G3 (Bethesda).. PMID: 37284815
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
1,6-Hexanediol, 500 g | sc-237791 | 500 g | $84.00 | |||
1,6-Hexanediol, 1 kg | sc-237791A | 1 kg | $90.00 | |||
1,6-Hexanediol, 2.5 kg | sc-237791B | 2.5 kg | $202.00 | |||
1,6-Hexanediol, 10 kg | sc-237791C | 10 kg | $764.00 | |||
1,6-Hexanediol, 50 kg | sc-237791D | 50 kg | $3000.00 |