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1,2,4,5-Tetramethylbenzene (CAS 95-93-2)

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Alternate Names:
Durene
CAS Number:
95-93-2
Molecular Weight:
134.22
Molecular Formula:
C10H14
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,2,4,5-tetramethylbenzene is a versatile aromatic hydrocarbon extensively employed in various industrial applications. This colorless, non-toxic, and faintly scented compound boasts a low vapor pressure and remarkable solubility in numerous organic solvents. Its significance in industry lies in its use for producing lubricants, fuel additives, and as an additive for coatings in plastics and rubber manufacturing. Moreover, it serves as a solvent for various organic compounds, such as dyes and pigments. Beyond industrial applications, 1,2,4,5-Tetramethylbenzene finds utility in laboratory experiments, particularly in the synthesis of organic compounds and in studying biochemical effects. The precise mechanism of action of 1,2,4,5-Tetramethylbenzene remains partially understood, but it is believed to arise from its interactions with various organic compounds. Notably, it can form complexes with diverse organic molecules, including proteins and nucleic acids.


1,2,4,5-Tetramethylbenzene (CAS 95-93-2) References

  1. [The hygienic evaluation of 1,2,4,5-tetramethylbenzene via inhalation body uptake].  |  Egorov, NN., et al. 1999. Gig Sanit. 5-7. PMID: 10349226
  2. Indirect NMR detection in solids with multiple cross-polarization periods.  |  Khitrin, AK. and Fung, BM. 2001. J Magn Reson. 152: 185-8. PMID: 11531378
  3. Azolium-linked cyclophanes: a comprehensive examination of conformations by 1H NMR spectroscopy and structural studies.  |  Baker, MV., et al. 2004. J Org Chem. 69: 7640-52. PMID: 15497992
  4. Low frequency internal modes of 1,2,4,5-tetramethylbenzene, tetramethylpyrazine and tetramethyl-1,4-benzoquinone INS, Raman, infrared and theoretical DFT studies.  |  Pawlukojć, A., et al. 2006. Spectrochim Acta A Mol Biomol Spectrosc. 63: 766-73. PMID: 16098791
  5. Observation of vibronic emission spectrum of jet-cooled duryl radical in corona excitation.  |  Lee, GW. and Lee, SK. 2007. J Chem Phys. 126: 214308. PMID: 17567197
  6. Physiologically-based toxicokinetic modeling of durene (1,2,3,5-tetramethylbenzene) and isodurene (1,2,4,5-tetramethylbenzene) in humans.  |  Jałowiecki, P. and Janasik, B. 2007. Int J Occup Med Environ Health. 20: 155-65. PMID: 17638682
  7. Validation of a gas chromatographic method to quantify sesquiterpenes in copaiba oils.  |  Sousa, JP., et al. 2011. J Pharm Biomed Anal. 54: 653-9. PMID: 21095089
  8. Rate constants for the reactions of OH radicals with 1,2,4,5-tetramethylbenzene, pentamethylbenzene, 2,4,5-trimethylbenzaldehyde, 2,4,5-trimethylphenol, and 3-methyl-3-hexene-2,5-dione and products of OH + 1,2,4,5-tetramethylbenzene.  |  Aschmann, SM., et al. 2013. J Phys Chem A. 117: 2556-68. PMID: 23495920
  9. Kinetic and mechanistic study of the reaction of OH radicals with methylated benzenes: 1,4-dimethyl-, 1,3,5-trimethyl-, 1,2,4,5-, 1,2,3,5- and 1,2,3,4-tetramethyl-, pentamethyl-, and hexamethylbenzene.  |  Alarcón, P., et al. 2015. Phys Chem Chem Phys. 17: 13053-65. PMID: 25913267
  10. Mini-Review on Structure-Reactivity Relationship for Aromatic Molecules: Recent Advances.  |  Galabov, B., et al. 2022. ACS Omega. 7: 8199-8208. PMID: 35309413
  11. Investigations on mechanisms, kinetics, and ecotoxicity in OH-initiated degradation of 1,2,4,5-tetramethylbenzene in the environment.  |  Zhao, H., et al. 2022. Environ Sci Pollut Res Int. 29: 84616-84628. PMID: 35788481
  12. Toxic effects of acute inhalation exposure to 1,2,4,5-tetramethylbenzene (durene) in experimental animals.  |  Korsak, Z., et al. 1998. Int J Occup Med Environ Health. 11: 267-72. PMID: 9844309

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,2,4,5-Tetramethylbenzene, 5 g

sc-237706
5 g
$41.00