Date published: 2026-4-28

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Valerophenone (CAS 1009-14-9)

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Alternate Names:
1-phenylpentan-1-one, Butyl phenyl ketone
CAS Number:
1009-14-9
Purity:
≥98%
Molecular Weight:
162.23
Molecular Formula:
C11H14O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Valerophenone, an aromatic ketone with a pentanoyl group attached to a benzene ring, exhibits significant chemical reactivity at the ketone group, rendering it a vital intermediate in organic synthesis. Its role extends to being a foundational component in compound creation, owing to its pivotal function in Friedel-Crafts acylation. Furthermore, Valerophenone serves as a key starting material for various chemical syntheses, utilizing its ketonic functionality to introduce complex side chains crucial for diverse compounds. Beyond organic synthesis, Valerophenone finds application in research and development of agrochemicals, leveraging its reactivity in aldol condensations and other carbon-carbon bond-forming reactions. Moreover, it is utilized in photochemical experiments due to its ability to absorb ultraviolet light, making it invaluable in studies related to photo-initiated polymerization processes.


Valerophenone (CAS 1009-14-9) References

  1. Cloning and analysis of valerophenone synthase gene expressed specifically in lupulin gland of hop (Humulus lupulus L.).  |  Okada, Y. and Ito, K. 2001. Biosci Biotechnol Biochem. 65: 150-5. PMID: 11272819
  2. Photodegradation of organic pollutants on the spruce needle wax surface under laboratory conditions.  |  Dolinová, J., et al. 2004. Chemosphere. 57: 1399-407. PMID: 15519385
  3. Methyl chloroacetate as an extraction solvent for coupling liquid-liquid semimicroextraction with micellar electrokinetic chromatography through on-capillary decomposition for the separation of neutral compounds with concentration enhancement.  |  Wang, T., et al. 2007. J Chromatogr A. 1147: 105-10. PMID: 17331520
  4. Inhibition of carbonyl reductase activity in pig heart by alkyl phenyl ketones.  |  Imamura, Y., et al. 2007. J Enzyme Inhib Med Chem. 22: 105-9. PMID: 17373555
  5. Solvent effects on photoreactivity of valerophenone: a combined QM and MM study.  |  Ding, L., et al. 2009. J Org Chem. 74: 8956-62. PMID: 19950879
  6. An extraction technique for analytical sample preparation in aqueous solution based on controlling dispersion of ionic surfactant assemblies in isotachophoretic migration.  |  Wang, T., et al. 2011. J Chromatogr A. 1218: 185-9. PMID: 21159349
  7. The reactivity of the 1,4-biradical formed by Norrish type reactions of aqueous valerophenone: a QM/MM-based FEP study.  |  Shen, L. and Fang, WH. 2011. J Org Chem. 76: 773-9. PMID: 21222478
  8. Photochemistry of 2-diphenylmethoxyacetophenone. Direct detection of a long-lived enol from a Norrish Type II photoreaction.  |  Sundaresan, AK., et al. 2011. Photochem Photobiol Sci. 10: 1450-4. PMID: 21512717
  9. Very high pressure liquid chromatography using fully porous particles: quantitative analysis of fast gradient separations without post-run times.  |  Stankovich, JJ., et al. 2014. J Chromatogr A. 1324: 155-63. PMID: 24296292
  10. Mass transport of small retained molecules in polymer-based monolithic columns.  |  Gritti, F. and Guiochon, G. 2014. J Chromatogr A. 1362: 49-61. PMID: 25179287
  11. The quantitative impact of the mesopore size on the mass transfer mechanism of the new 1.9 μm fully porous Titan-C18 particles II--analysis of biomolecules.  |  Gritti, F. and Guiochon, G. 2015. J Chromatogr A. 1392: 10-9. PMID: 25798869
  12. Achieving a Peak Capacity of 1800 Using an 8 m Long Pillar Array Column.  |  Baca, M., et al. 2019. Anal Chem. 91: 10932-10936. PMID: 31411861
  13. Simulation of elution profiles in liquid chromatography - IV: Experimental characterization and modeling of solute injection profiles from a modulation valve used in two-dimensional liquid chromatography.  |  Weatherbee, SL., et al. 2020. J Chromatogr A. 1626: 461373. PMID: 32797851
  14. Liquid chromatography coupled with photodiode array and a multivariate curve resolution - Alternating least square algorithm for identification and quantification of co-eluting impurities in pharmaceutical analysis.  |  Vecchietti, D., et al. 2022. J Chromatogr A. 1678: 463364. PMID: 35914409
  15. A simple Norrish Type II actinometer for flow photoreactions.  |  Yaghmaei, M. and Scaiano, JC. 2023. Photochem Photobiol Sci.. PMID: 37069424

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Valerophenone, 10 g

sc-237408
10 g
$20.00