Molecular structure of (+)-Valencene, CAS Number: 4630-07-3
(+)-Valencene (CAS 4630-07-3)
Alternate Names:
(3R,4aS,5R)-4a,5-Dimethyl-3-isopropenyl-1,2,3,4,4a,5,6,7-octahydronaphthalene
Application:
(+)-Valencene is an aroma component of citrus fruit and citrus-derived odorants
CAS Number:
4630-07-3
Purity:
≥70%
Molecular Weight:
204.35
Molecular Formula:
C15H24
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
(+)-Valencene is a sesquiterpene that is an aroma component of citrus fruit and citrus-derived odorants. (+)-Valencene is biosynthesized from FPP by the CVS enzyme. It is a precursor to nootkatone, the main contributor to the aroma and flavor of grapefruit. Within the cell, (+)-Valencene is primarily located in the membrane (predicted from logP) and cytoplasm. It can also be found in burdock. This makes (+)-Valencene a potential biomarker for the consumption of this plant.
(+)-Valencene (CAS 4630-07-3) References
- Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3. | Sowden, RJ., et al. 2005. Org Biomol Chem. 3: 57-64. PMID: 15602599
- Nootkatone--a biotechnological challenge. | Fraatz, MA., et al. 2009. Appl Microbiol Biotechnol. 83: 35-41. PMID: 19333595
- Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system. | Girhard, M., et al. 2009. Microb Cell Fact. 8: 36. PMID: 19591681
- A chicory cytochrome P450 mono-oxygenase CYP71AV8 for the oxidation of (+)-valencene. | Cankar, K., et al. 2011. FEBS Lett. 585: 178-82. PMID: 21115006
- Challenges and pitfalls of P450-dependent (+)-valencene bioconversion by Saccharomyces cerevisiae. | Gavira, C., et al. 2013. Metab Eng. 18: 25-35. PMID: 23518241
- Production of the sesquiterpene (+)-valencene by metabolically engineered Corynebacterium glutamicum. | Frohwitter, J., et al. 2014. J Biotechnol. 191: 205-13. PMID: 24910970
- (+)-Valencene production in Nicotiana benthamiana is increased by down-regulation of competing pathways. | Cankar, K., et al. 2015. Biotechnol J. 10: 180-9. PMID: 25159317
- CitAP2.10 activation of the terpene synthase CsTPS1 is associated with the synthesis of (+)-valencene in 'Newhall' orange. | Shen, SL., et al. 2016. J Exp Bot. 67: 4105-15. PMID: 27194737
- Cell-free one-pot conversion of (+)-valencene to (+)-nootkatone by a unique dye-decolorizing peroxidase combined with a laccase from Funalia trogii. | Kolwek, J., et al. 2018. J Ind Microbiol Biotechnol. 45: 89-101. PMID: 29270883
- Coupling cell growth and biochemical pathway induction in Saccharomyces cerevisiae for production of (+)-valencene and its chemical conversion to (+)-nootkatone. | Ye, Z., et al. 2022. Metab Eng. 72: 107-115. PMID: 35296429
- Genomic and transcriptomic analysis screening key genes for (+)-valencene biotransformation to (+)-nootkatone in Yarrowia lipolytica. | Li, X., et al. 2022. Microbiol Res. 260: 127042. PMID: 35483313
- Stepwise engineering of Saccharomyces cerevisiae to produce (+)-valencene and its related sesquiterpenes. | Ouyang, X., et al. 2019. RSC Adv. 9: 30171-30181. PMID: 35530214
- Global Metabolic Rewiring of Yeast Enables Overproduction of Sesquiterpene (+)-Valencene. | Cao, C., et al. 2022. J Agric Food Chem. 70: 7180-7187. PMID: 35657170
- Differential proteomic analysis of citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. | Li, X., et al. 2022. Int J Biol Macromol. 220: 1031-1048. PMID: 35961559
- Isolation, purification, and mass spectrometry identification of the enzyme involved in citrus flavor (+)-valencene biotransformation to (+)-nootkatone by Yarrowia lipolytica. | Li, X., et al. 2023. J Sci Food Agric.. PMID: 36897036
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Valencene, 10 g | sc-237407 | 10 g | $143.00 | |||
(+)-Valencene, 50 g | sc-237407A | 50 g | $275.00 |