Date published: 2025-10-15

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(+)-Menthofuran (CAS 17957-94-7)

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Alternate Names:
(R)-3,6-Dimethyl-4,5,6,7-tetrahydrobenzofuran
CAS Number:
17957-94-7
Purity:
≥99%
Molecular Weight:
150.22
Molecular Formula:
C10H14O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(+)-Menthofuran is utilized as an insecticide, and an antimicrobial substance. It is integral in the production of compounds like menthol, menthone, and isomenthone. It is suggested to affect various cellular signaling cascades. Research indicates that (+)-Menthofuran can impede the activity of certain enzymes, such as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX). Furthermore, there is evidence pointing to its capability to stimulate transient receptor potential (TRP) channels associated with sensing pain and thermal changes.


(+)-Menthofuran (CAS 17957-94-7) References

  1. Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene.  |  Bertea, CM., et al. 2001. Arch Biochem Biophys. 390: 279-86. PMID: 11396930
  2. Effect of Mentha x piperita essential oil and monoterpenes on cucumber root membrane potential.  |  Maffei, M., et al. 2001. Phytochemistry. 58: 703-7. PMID: 11672734
  3. In vitro metabolism of (-)-camphor using human liver microsomes and CYP2A6.  |  Gyoubu, K. and Miyazawa, M. 2007. Biol Pharm Bull. 30: 230-3. PMID: 17268056
  4. Volatile terpenoids of endophyte-free and infected peppermint (Mentha piperita L.): chemical partitioning of a symbiosis.  |  Mucciarelli, M., et al. 2007. Microb Ecol. 54: 685-96. PMID: 17370029
  5. A systems biology approach identifies the biochemical mechanisms regulating monoterpenoid essential oil composition in peppermint.  |  Rios-Estepa, R., et al. 2008. Proc Natl Acad Sci U S A. 105: 2818-23. PMID: 18287058
  6. Metabolism of (+)- and (-)-menthols by CYP2A6 in human liver microsomes.  |  Miyazawa, M., et al. 2011. J Oleo Sci. 60: 127-32. PMID: 21343660
  7. Improving peppermint essential oil yield and composition by metabolic engineering.  |  Lange, BM., et al. 2011. Proc Natl Acad Sci U S A. 108: 16944-9. PMID: 21963983
  8. Determination of cytochrome P450 enzymes involved in the metabolism of (-)-terpinen-4-ol by human liver microsomes.  |  Miyazawa, M. and Haigou, R. 2011. Xenobiotica. 41: 1056-62. PMID: 22054099
  9. Quantitative comparative analysis of the bio-active and toxic constituents of leaves and spikes of Schizonepeta tenuifolia at different harvesting times.  |  Yu, S., et al. 2011. Int J Mol Sci. 12: 6635-44. PMID: 22072908
  10. In vitro and in vivo peppermint (Mentha piperita) growth promotion by nonmycorrhizal fungal colonization.  |  Mucciarelli, M., et al. 2003. New Phytol. 158: 579-591. PMID: 36056516

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(+)-Menthofuran, 1 ml

sc-235586
1 ml
$144.00

(+)-Menthofuran, 5 ml

sc-235586A
5 ml
$450.00