Molecular structure of L-Leucine-1-13C, CAS Number: 74292-94-7
L-Leucine-1-13C (CAS 74292-94-7)
CAS Number:
74292-94-7
Molecular Weight:
132.17
Molecular Formula:
(13C)C5H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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L-Leucine-1-13C is a stable isotope of L-leucine, an amino acid that plays a key role in protein synthesis. As a labeled compound, L-Leucine-1-13C is used in metabolic studies and tracer experiments to track the fate of leucine in biological systems. It is employed to investigate the kinetics of protein turnover, the regulation of muscle protein synthesis, and the metabolism of amino acids in various tissues. This labeled compound allows for the precise quantification of leucine flux and turnover rates, providing insights into cellular metabolism and protein dynamics. In experimental applications, L-Leucine-1-13C serves powerful for studying the metabolic fate of leucine and its role in protein homeostasis.
L-Leucine-1-13C (CAS 74292-94-7) References
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- Novel isotopic N,N-dimethyl leucine (iDiLeu) reagents enable absolute quantification of peptides and proteins using a standard curve approach. | Greer, T., et al. 2015. J Am Soc Mass Spectrom. 26: 107-19. PMID: 25377360
- Effects of Rice Straw Supplemented with Urea and Molasses on Intermediary Metabolism of Plasma Glucose and Leucine in Sheep. | Alam, MK., et al. 2016. Asian-Australas J Anim Sci. 29: 523-9. PMID: 26949953
- Co-Localization of Insulin-Like Growth Factor Binding Protein-1, Casein Kinase-2β, and Mechanistic Target of Rapamycin in Human Hepatocellular Carcinoma Cells as Demonstrated by Dual Immunofluorescence and in Situ Proximity Ligation Assay. | Singal, SS., et al. 2018. Am J Pathol. 188: 111-124. PMID: 29037858
- A Python-Based Pipeline for Preprocessing LC-MS Data for Untargeted Metabolomics Workflows. | Riquelme, G., et al. 2020. Metabolites. 10: PMID: 33081373
- Human Plasma Metabolomics for Biomarker Discovery: Targeting the Molecular Subtypes in Breast Cancer. | Díaz-Beltrán, L., et al. 2021. Cancers (Basel). 13: PMID: 33466323
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
L-Leucine-1-13C, 1 g | sc-235475 | 1 g | $229.00 |