Molecular structure of Isovitexin, CAS Number: 38953-85-4
Isovitexin (CAS 38953-85-4)
Alternate Names:
Saponaretin
Application:
Isovitexin is a phytochemical with antioxidant properties
CAS Number:
38953-85-4
Molecular Weight:
432.38
Molecular Formula:
C21H20O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isovitexin, a member of the flavone family, exhibits antioxidant and antimicrobial properties, along with playing a role in the modulation of inflammation and cellular proliferation. Also can cause reduction of inflammatory mediators, neutralizing free radicals, and affecting the proliferation of cells. It is often used as a marker to investigate the phytochemical composition of plants and to understand their metabolic pathways. In the field of chemistry, is studied for its role in plant pigmentation and its interactions with other plant compounds.
Isovitexin (CAS 38953-85-4) References
- A review on the pharmacological effects of vitexin and isovitexin. | He, M., et al. 2016. Fitoterapia. 115: 74-85. PMID: 27693342
- Isovitexin alleviates liver injury induced by lipopolysaccharide/d-galactosamine by activating Nrf2 and inhibiting NF-κB activation. | Hu, JJ., et al. 2018. Microb Pathog. 119: 86-92. PMID: 29604422
- Isovitexin reduces carcinogenicity and stemness in hepatic carcinoma stem-like cells by modulating MnSOD and FoxM1. | Cao, X., et al. 2019. J Exp Clin Cancer Res. 38: 264. PMID: 31208440
- Isovitexin Increases Stem Cell Properties and Protects Against PM2.5 in Keratinocytes. | Chowjarean, V., et al. 2019. In Vivo. 33: 1833-1841. PMID: 31662510
- Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses. | Liu, S., et al. 2020. Int Immunopharmacol. 83: 106437. PMID: 32222637
- Isovitexin Suppresses Stemness of Lung Cancer Stem-Like Cells through Blockage of MnSOD/CaMKII/AMPK Signaling and Glycolysis Inhibition. | Liu, F., et al. 2021. Biomed Res Int. 2021: 9972057. PMID: 34195288
- Isovitexin attenuates tumor growth in human colon cancer cells through the modulation of apoptosis and epithelial-mesenchymal transition via PI3K/Akt/mTOR signaling pathway. | Zhu, H., et al. 2021. Biochem Cell Biol. 99: 741-749. PMID: 34219464
- Isovitexin Is a Direct Inhibitor of Staphylococcus aureus Coagulase. | Xiang, H., et al. 2021. J Microbiol Biotechnol. 31: 1350-1357. PMID: 34409949
- Isovitexin Inhibits Ginkgolic Acids-Induced Inflammation Through Downregulating SHP2 Activation. | Zhang, Y., et al. 2021. Front Pharmacol. 12: 630320. PMID: 34456714
- Isovitexin alleviates acute gouty arthritis in rats by inhibiting inflammation via the TLR4/MyD88/NF-κB pathway. | Sun, X., et al. 2021. Pharm Biol. 59: 1326-1333. PMID: 34582722
- Isovitexin protects against acute liver injury by targeting PTEN, PI3K and BiP via modification of m6A. | Huang, Y., et al. 2022. Eur J Pharmacol. 917: 174749. PMID: 35007522
- Oral Administration of Isovitexin, a Naturally Occurring Apigenin Derivative Showed Osteoanabolic Effect in Ovariectomized Mice: A Comparative Study with Teriparatide. | Pal, S., et al. 2022. Calcif Tissue Int. 111: 196-210. PMID: 35451627
- Isovitexin Protects Mice from Methicillin-Resistant Staphylococcus aureus-Induced Pneumonia by Targeting Sortase A. | Tian, L., et al. 2022. J Microbiol Biotechnol. 32: 1284-1291. PMID: 36224754
- Regulatory effect of isovitexin on MAPK/NF-κB signal in mice with acute ulcerative colitis. | Liu, MX., et al. 2022. J Asian Nat Prod Res. 1-18. PMID: 36394271
- Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells. | Ghanbari-Movahed, M., et al. 2023. Metabolites. 13: PMID: 36984844
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MPO.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isovitexin, 1 mg | sc-235430 | 1 mg | $198.00 |