Molecular structure of Ginsenoside Rf, CAS Number: 52286-58-5
Ginsenoside Rf (CAS 52286-58-5)
Application:
Ginsenoside Rf is a glycoside found to mediate lipoprotein metabolism
CAS Number:
52286-58-5
Molecular Weight:
801.01
Molecular Formula:
C42H72O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ginsenoside Rf, a glycoside of protopanaxatriol (sc-204866) from Panax ginseng, is shown to be a biologically active saponin found to regulate lipoprotein metabolism. Mechanistic studies report that this regulation is done via altering of peroxisome proliferator-activated receptor α (PPARα)-mediated pathways. PPARα has demonstrated the ability to regulate C-III mRNA and basal levels of hepatic apoA-I (apolipoprotein A-I) which affect lipoprotein metabolism. Additional experiments have also observed this Ginsenoside Rf's ability to inhibit Ca2+ channels in mammalian sensory neurons in vitro.
Ginsenoside Rf (CAS 52286-58-5) References
- Ginsenoside Rf, a component of ginseng, regulates lipoprotein metabolism through peroxisome proliferator-activated receptor alpha. | Lee, H., et al. 2006. Biochem Biophys Res Commun. 339: 196-203. PMID: 16297877
- Ginsenoside Rf inhibits human tau proteotoxicity and causes specific LncRNA, miRNA and mRNA expression changes in Caenorhabditis elegans model of tauopathy. | Zhang, S., et al. 2022. Eur J Pharmacol. 922: 174887. PMID: 35306001
- Ginsenoside Rf Enhances Exercise Endurance by Stimulating Myoblast Differentiation and Mitochondrial Biogenesis in C2C12 Myotubes and ICR Mice. | Lim, WC., et al. 2022. Foods. 11: PMID: 35741909
- Therapeutic Mechanism and Key Active Ingredients of Shenfu Injection in Sepsis: A Network Pharmacology and Molecular Docking Approach. | Yuan, H., et al. 2022. Evid Based Complement Alternat Med. 2022: 9686149. PMID: 36062176
- Bioconversion of Ginsenoside Rf into Its Hydrated Derivative with Elevated Anti-inflammatory Effect by a Highly Specific Biocatalytic System of Cordyceps Sinensis. | Liu, J., et al. 2023. Chem Biodivers. 20: e202200421. PMID: 36867116
- Untargeted Metabolomic Analysis and Chemometrics to Identify Potential Marker Compounds for the Chemical Differentiation of Panax ginseng, P. quinquefolius, P. notoginseng, P. japonicus, and P. japonicus var. major. | Ji, R., et al. 2023. Molecules. 28: PMID: 36985717
- Integrated serum pharmacochemistry and metabolomics reveal potential effective components and mechanisms of Shengjiang Xiexin decoction in the treatment of Clostridium difficile infection. | Cui, Y., et al. 2023. Heliyon. 9: e15602. PMID: 37206044
- Network analysis to explore the pharmacological mechanism of Shenmai injection in treating granulocytopenia and evidence-based medicine approach validation. | Hou, X., et al. 2023. Medicine (Baltimore). 102: e33825. PMID: 37335746
- Ginsenoside Rf in wild ginseng adventitious roots extract inhibits melanogenesis via cAMP/PKA and NO/cGMP signalling pathways in α-melanocyte-stimulating hormone-stimulated B16F10 mouse melanoma cells and zebrafish. | Chen, H., et al. 2024. Nat Prod Res. 1-8. PMID: 38318698
- Jiangu formula: A novel osteoclast-osteoblast coupling agent for effective osteoporosis treatment. | Xu, H., et al. 2024. Phytomedicine. 128: 155501. PMID: 38471318
- Detection of Adulterated Naodesheng Tablet (Naodesheng Pian) via In-Depth Chemical Analysis and Subsequent Reconstruction of Its Pharmacopoeia Q-Markers. | Li, C., et al. 2024. Molecules. 29: PMID: 38543029
- Ginsenoside Rf, a trace component of ginseng root, produces antinociception in mice. | Mogil, JS., et al. 1998. Brain Res. 792: 218-28. PMID: 9593902
- Determination of ginsenoside Rf and Rg2 from Panax ginseng using enzyme immunoassay. | Yoon, SR., et al. 1998. Chem Pharm Bull (Tokyo). 46: 1144-7. PMID: 9692222
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GROγ.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ginsenoside Rf, 5 mg | sc-235250 | 5 mg | $280.00 |