Date published: 2025-10-4

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Diflufenican (CAS 83164-33-4)

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Alternate Names:
N-(2,4-Difluorophenyl)-2-(3-(trifluoromethyl)phenoxy)nicotinamide
Application:
Diflufenican is an agricultural herbicide
CAS Number:
83164-33-4
Molecular Weight:
394.29
Molecular Formula:
C19H11F5N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Diflufenican is a herbicide that functions by inhibiting the enzyme protoporphyrinogen oxidase (PPO), which is essential for chlorophyll biosynthesis in plants. By targeting this specific enzyme, diflufenican disrupts the normal growth and development of susceptible plants, leading to chlorosis and ultimately plant death. Diflufenican′s mechanism of action involves binding to the active site of PPO, preventing the enzyme from carrying out its normal function in the synthesis of chlorophyll. As a result, the affected plants are unable to produce chlorophyll, leading to a loss of photosynthetic capacity and subsequent death. In this way, diflufenican may play a role in inhibiting the growth of unwanted plants in agricultural and horticultural applications, which may be useful for weed control in various experimental applications.


Diflufenican (CAS 83164-33-4) References

  1. Soil dissipation of diuron, chlorotoluron, simazine, propyzamide, and diflufenican herbicides after repeated applications in fruit tree orchards.  |  Rouchaud, J., et al. 2000. Arch Environ Contam Toxicol. 39: 60-5. PMID: 10790503
  2. Spatial variation in the degradation rate of the pesticides isoproturon, azoxystrobin and diflufenican in soil and its relationship with chemical and microbial properties.  |  Bending, GD., et al. 2006. Environ Pollut. 139: 279-87. PMID: 16043274
  3. The effect of diflufenican on lipid metabolism in plants.  |  Ashton, IP., et al. 1991. Biochem Soc Trans. 19: 320S. PMID: 1838339
  4. Evolution of soil biological properties after addition of glyphosate, diflufenican and glyphosate+diflufenican herbicides.  |  Tejada, M. 2009. Chemosphere. 76: 365-73. PMID: 19376558
  5. Single drop microextraction and gas chromatography-mass spectrometry for the determination of diflufenican, mepanipyrim, fipronil, and pretilachlor in water samples.  |  Araujo, L., et al. 2013. Environ Monit Assess. 185: 10225-33. PMID: 23887887
  6. The mechanism of diflufenican resistance and its inheritance in oriental mustard (Sisymbrium orientale L.) from Australia.  |  Dang, HT., et al. 2018. Pest Manag Sci. 74: 1279-1285. PMID: 29330913
  7. Cross-resistance to diflufenican and picolinafen and its inheritance in oriental mustard (Sisymbrium orientale L.).  |  Dang, HT., et al. 2019. Pest Manag Sci. 75: 195-203. PMID: 29799165
  8. Effect of diflufenican on total carotenoid and phytoene production in carrot suspension-cultured cells.  |  Miras-Moreno, B., et al. 2019. Planta. 249: 113-122. PMID: 30083808
  9. Assessing herbicide symptoms by using a logarithmic field sprayer.  |  Cunha, BRD., et al. 2019. Pest Manag Sci. 75: 1166-1171. PMID: 30379393
  10. A comparison of the fate of diflufenican in agricultural sandy soil and gravel used in urban areas.  |  Svendsen, SB., et al. 2020. Sci Total Environ. 715: 136803. PMID: 32069738
  11. Determination of residue of diflufenican in wheat and soil by ultra-high-pressure liquid chromatography and mass spectrometry conditions.  |  Hu, Z., et al. 2021. J Sci Food Agric. 101: 215-219. PMID: 32623721
  12. Leaching of herbicidal residues from gravel surfaces - A lysimeter-based study comparing gravels with agricultural topsoil.  |  Albers, CN., et al. 2020. Environ Pollut. 266: 115225. PMID: 32795764
  13. Non-Target-Site Resistance Mechanisms Endow Multiple Herbicide Resistance to Five Mechanisms of Action in Conyza bonariensis.  |  Palma-Bautista, C., et al. 2021. J Agric Food Chem. 69: 14792-14801. PMID: 34852464
  14. Determination of diflufenican and azaconazole pesticides in wastewater samples by GC-MS after preconcentration with stearic acid functionalized magnetic nanoparticles-based dispersive solid-phase extraction.  |  Metin, B., et al. 2022. Environ Monit Assess. 195: 32. PMID: 36284003
  15. Phenotypic and transcriptomic acclimation of the green microalga Raphidocelis subcapitata to high environmental levels of the herbicide diflufenican.  |  Gómez-Martínez, D., et al. 2023. Sci Total Environ. 875: 162604. PMID: 36878298

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Diflufenican, 100 mg

sc-234684
100 mg
$90.00