Molecular structure of Asiatic acid, CAS Number: 464-92-6
Asiatic acid (CAS 464-92-6)
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Alternate Names:
2α,23-Dihydroxyursolic acid; Dammarolic acid
Application:
Asiatic acid is a pentacyclic triterpene that is known to stimulate wound healing by increasing collagen production
CAS Number:
464-92-6
Molecular Weight:
488.70
Molecular Formula:
C30H48O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Asiatic acid is a pentacyclic triterpene. In vitro studies have shown remarkable anti-inflammatory, antioxidant, and anti-aging properties. Notably, it exhibits the ability to mitigate the production of pro-inflammatory cytokines and alleviate oxidative damage in cultured cells. Moreover, asiatic acid exhibits the capacity to suppress the formation of free radicals and enhance cell viability in cultured cells, thereby showcasing its beneficial effects. Asiatic acid is a p38 activator.
Asiatic acid (CAS 464-92-6) References
- Asiatic acid derivatives protect cultured cortical neurons from glutamate-induced excitotoxicity. | Lee, MK., et al. 2000. Res Commun Mol Pathol Pharmacol. 108: 75-86. PMID: 11758977
- Asiatic acid, a triterpene, induces apoptosis through intracellular Ca2+ release and enhanced expression of p53 in HepG2 human hepatoma cells. | Lee, YS., et al. 2002. Cancer Lett. 186: 83-91. PMID: 12183079
- Inhibition of ultraviolet-A-modulated signaling pathways by asiatic acid and ursolic acid in HaCaT human keratinocytes. | Soo Lee, Y., et al. 2003. Eur J Pharmacol. 476: 173-8. PMID: 12969763
- Mechanism underlying mitochondrial protection of asiatic acid against hepatotoxicity in mice. | Gao, J., et al. 2006. J Pharm Pharmacol. 58: 227-33. PMID: 16451751
- Protective effects of asiatic acid on rotenone- or H2O2-induced injury in SH-SY5Y cells. | Xiong, Y., et al. 2009. Neurochem Res. 34: 746-54. PMID: 18802751
- Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia. | Krishnamurthy, RG., et al. 2009. J Neurosci Res. 87: 2541-50. PMID: 19382233
- Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin-induced diabetic rats. | Liu, J., et al. 2010. Diabetes Metab Res Rev. 26: 448-54. PMID: 20809533
- Effects of asiatic acid on passive and active avoidance task in male Spraque-Dawley rats. | Nasir, MN., et al. 2011. J Ethnopharmacol. 134: 203-9. PMID: 21167268
- Antinociceptive activities and the mechanisms of anti-inflammation of asiatic Acid in mice. | Huang, SS., et al. 2011. Evid Based Complement Alternat Med. 2011: 895857. PMID: 21584194
- Effects of Asiatic Acid on Spatial Working Memory and Cell Proliferation in the Adult Rat Hippocampus. | Sirichoat, A., et al. 2015. Nutrients. 7: 8413-23. PMID: 26445061
- Neuroprotective effect of asiatic acid against spinal cord injury in rats. | Jiang, W., et al. 2016. Life Sci. 157: 45-51. PMID: 27153777
- Asiatic acid inhibits lung cancer cell growth in vitro and in vivo by destroying mitochondria. | Wu, T., et al. 2017. Acta Pharm Sin B. 7: 65-72. PMID: 28119810
- Neuroprotective role of Asiatic acid in aluminium chloride induced rat model of Alzheimer's disease. | Ahmad Rather, M., et al. 2018. Front Biosci (Schol Ed). 10: 262-275. PMID: 28930532
Activator of:
p38.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Asiatic acid, 100 mg | sc-233894B | 100 mg | $190.00 | |||
Asiatic acid, 500 mg | sc-233894 | 500 mg | $296.00 | |||
Asiatic acid, 5 g | sc-233894A | 5 g | $2045.00 |