Date published: 2025-10-14

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α-Pinene (CAS 80-56-8)

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Alternate Names:
(±)-2-Pinene, 2,6,6-Trimethylbicyclo[3.1.1]hept-2-ene, alpha-Pinene; 4,6,6-trimethylbicyclo[3.1.1]hept-3-ene
Application:
α-Pinene is a standard in headspace solid-phase microextraction-gas chromatographic analysis
CAS Number:
80-56-8
Purity:
≥97%
Molecular Weight:
136.23
Molecular Formula:
C10H16
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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α-Pinene is a bicyclic monoterpene, found in the essential oils of many types of plants and trees, that is of interest in the field of organic chemistry due to its role as a chiral synthetic intermediate. It is explored for its use in the synthesis of a variety of terpenoid compounds. α-Pinene is also studied for its ability to form other structurally complex molecules through reactions such as oxidation or rearrangement. In materials science, α-Pinene is used as a starting material for the synthesis of polymers and other organic materials that are derived from renewable resources. Additionally, the compound is studied in atmospheric chemistry for its role in the formation of aerosols and potential impact on air quality. The research into the transformation of α-Pinene by environmental factors contributes to a broader understanding of biogenic volatile organic compounds (VOCs) in the atmosphere.


α-Pinene (CAS 80-56-8) References

  1. Metabolic engineering of Escherichia coli for the biosynthesis of alpha-pinene.  |  Yang, J., et al. 2013. Biotechnol Biofuels. 6: 60. PMID: 23631625
  2. α-Pinene Inhibits Human Prostate Cancer Growth in a Mouse Xenograft Model.  |  Zhao, Y., et al. 2018. Chemotherapy. 63: 1-7. PMID: 29069647
  3. Racemic and Enantiopure Camphene and Pinene Studied by the Crystalline Sponge Method.  |  de Poel, W., et al. 2018. Cryst Growth Des. 18: 126-132. PMID: 29317854
  4. α-pinene regulates miR-221 and induces G2/M phase cell cycle arrest in human hepatocellular carcinoma cells.  |  Xu, Q., et al. 2018. Biosci Rep. 38: PMID: 30473536
  5. Attenuation Effects of Alpha-Pinene Inhalation on Mice with Dizocilpine-Induced Psychiatric-Like Behaviour.  |  Ueno, H., et al. 2019. Evid Based Complement Alternat Med. 2019: 2745453. PMID: 31467573
  6. α-Pinene Induces Apoptotic Cell Death via Caspase Activation in Human Ovarian Cancer Cells.  |  Hou, J., et al. 2019. Med Sci Monit. 25: 6631-6638. PMID: 31482864
  7. The Effects of Frankincense Essential Oil on Stress in Rats.  |  Okano, S., et al. 2019. J Oleo Sci. 68: 1003-1009. PMID: 31582666
  8. Alpha-pinene promotes osteoblast differentiation and attenuates TNFα-induced inhibition of differentiation in MC3T3-E1 pre-osteoblasts.  |  Min, HY., et al. 2020. Clin Exp Pharmacol Physiol. 47: 831-837. PMID: 31883130
  9. Wound Healing Activity of α-Pinene and α-Phellandrene.  |  Salas-Oropeza, J., et al. 2021. Molecules. 26: PMID: 33923276
  10. Antibiotic potentiating action of α-PINENE and borneol against EPEC and ETEC sorotypes.  |  Leite-Sampaio, NF., et al. 2022. Microb Pathog. 162: 105371. PMID: 34952151
  11. Thermal stability and oxidation characteristics of α-pinene, β-pinene and α-pinene/β-pinene mixture.  |  Liu, P., et al. 2021. RSC Adv. 11: 20529-20540. PMID: 35479917
  12. Heterogeneous Reactions of α-Pinene on Mineral Surfaces: Formation of Organonitrates and α-Pinene Oxidation Products.  |  Hettiarachchi, E. and Grassian, VH. 2022. J Phys Chem A. 126: 4068-4079. PMID: 35709385
  13. α-Pinene inhibits the growth of cervical cancer cells through its proapoptotic activity by regulating the miR-34a-5p/Bcl-2 signaling axis.  |  Huang, X., et al. 2022. Drug Dev Res. 83: 1766-1776. PMID: 36074793
  14. α-Pinene Influence on Pulpal Pain-Induced Learning and Memory Impairment in Rats Via Modulation of the GABAA Receptor.  |  Rafie, F., et al. 2022. Adv Biomed Res. 11: 60. PMID: 36124022
  15. Effects of super-class cannabis terpenes beta-caryophyllene and alpha-pinene on zebrafish behavioural biomarkers.  |  Johnson, A., et al. 2022. Sci Rep. 12: 17250. PMID: 36241680

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

α-Pinene, 5 ml

sc-233784
5 ml
$51.00

α-Pinene, 250 ml

sc-233784A
250 ml
$113.00