Date published: 2025-11-20

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3-Hydroxythiophenol (CAS 40248-84-8)

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Alternate Names:
3-Mercaptophenol
CAS Number:
40248-84-8
Molecular Weight:
126.18
Molecular Formula:
C6H6OS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Mercaptophenol is a chemical compound that functions as a nucleophilic reagent in organic synthesis. It acts as a thiol, participating in nucleophilic substitution reactions with electrophiles. 3-Mercaptophenol′s mechanism of action involves the sulfur atom attacking the electrophilic center of the substrate, leading to the formation of a new covalent bond. In this way, 3-Mercaptophenol can be used to introduce a thiol group into various organic molecules, allowing for the synthesis of sulfur-containing compounds. Its reactivity as a nucleophile may be useful in the modification of organic molecules, enabling the creation of new chemical entities.


3-Hydroxythiophenol (CAS 40248-84-8) References

  1. Modular asymmetric synthesis of aigialomycin D, a kinase-inhibitory scaffold.  |  Barluenga, S., et al. 2006. Angew Chem Int Ed Engl. 45: 3951-4. PMID: 16683294
  2. Chemical Synthesis of O-Glycosylated Human Interleukin-2 by the Reverse Polarity Protection Strategy.  |  Asahina, Y., et al. 2015. Angew Chem Int Ed Engl. 54: 8226-30. PMID: 26012897
  3. Development of amino- and dimethylcarbamate-substituted resorcinol as programmed cell death-1 (PD-1) inhibitor.  |  Liu, A., et al. 2016. Eur J Pharm Sci. 88: 50-8. PMID: 27063329
  4. One-Pot Four-Segment Ligation Using Seleno- and Thioesters: Synthesis of Superoxide Dismutase.  |  Takei, T., et al. 2017. Angew Chem Int Ed Engl. 56: 15708-15711. PMID: 29048715
  5. On-demand quantitative SERS bioassays facilitated by surface-tethered ratiometric probes.  |  Zhang, K., et al. 2018. Chem Sci. 9: 8089-8093. PMID: 30542557
  6. A lysosome-targeted near-infrared fluorescent probe for imaging endogenous cysteine (Cys) in living cells.  |  Cai, S., et al. 2020. J Mater Chem B. 8: 2269-2274. PMID: 32100785
  7. A novel ratiometric SERS biosensor with one Raman probe for ultrasensitive microRNA detection based on DNA hydrogel amplification.  |  He, Y., et al. 2019. J Mater Chem B. 7: 2643-2647. PMID: 32254997
  8. Single Alkali Metal Ion-Activated Porous Carbon With Heteroatom Doping for Supercapacitor Electrode.  |  Wang, C. 2020. Front Chem. 8: 815. PMID: 33102437
  9. Chemical synthesis of ferredoxin with 4 selenocysteine residues using a segment condensation method.  |  Takei, T., et al. 2020. Chem Commun (Camb). 56: 14239-14242. PMID: 33118552
  10. Rational design of a large Stokes shift xanthene-benzothiozolium dyad for probing cysteine in mitochondria.  |  Cai, S., et al. 2022. J Mater Chem B. 10: 1265-1271. PMID: 35129190
  11. A near-infrared and lager stocks shift xanthene-indolium sensor for probing hydrazine in mitochondria  |  Z Wang, Q Liu, S Cai, C Liu, S He, L Zhao, X Zeng… - Dyes and …, 2022 - Elsevier. July 2022,. Dyes and Pigments. Volume 203,: 110382.
  12. A convenient synthesis of 6,6′-dialkoxythioindigo dyes suitable for doping into a liquid crystal host  |  . 10 October 1994,. Tetrahedron Letters. Volume 35, Issue 41,: Pages 7549-7552.
  13. Catalytic alkane transfer-dehydrogenation by PSCOP iridium pincer complexes  |  W Yao, X Jia, X Leng, AS Goldman, M Brookhart… - Polyhedron, 2016 - Elsevier. 25 September 2016,. Polyhedron. Volume 116,: Pages 12-19.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Hydroxythiophenol, 1 g

sc-231784
1 g
$27.00