Date published: 2025-11-3

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Lysergol (CAS 602-85-7)

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CAS Number:
602-85-7
Molecular Weight:
254.33
Molecular Formula:
C16H18N2O
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Lysergol is a naturally occurring compound categorized as an amide. It is derived from ergot, a fungus that grows on rye. Lysergol is known for its inhibitory effect on Escherichia coli when combined with the antibiotic nalidixic acid. Lysergol possesses noteworthy biological properties, including receptor activity and control analysis.


Lysergol (CAS 602-85-7) References

  1. Total synthesis of (+/-)-lysergic acid, lysergol, and isolysergol by palladium-catalyzed domino cyclization of amino allenes bearing a bromoindolyl group.  |  Inuki, S., et al. 2008. Org Lett. 10: 5239-42. PMID: 18956869
  2. Changes in concentrations of lysergol in urine and prolactin in plasma, rectal temperature and respiration rate in sheep selected for resistance or susceptibility to ryegrass staggers and fed ergovaline.  |  Gooneratne, SR., et al. 2011. N Z Vet J. 59: 233-8. PMID: 21851300
  3. Quantitative determination of bioactive alkaloids lysergol and chanoclavine in Ipomoea muricata by reversed-phase high-performance liquid chromatography.  |  Maurya, A., et al. 2012. Biomed Chromatogr. 26: 1096-100. PMID: 22120837
  4. Simultaneous quantification of berberine and lysergol by HPLC-UV: evidence that lysergol enhances the oral bioavailability of berberine in rats.  |  Patil, S., et al. 2012. Biomed Chromatogr. 26: 1170-5. PMID: 22213237
  5. Antibacterial and synergy of clavine alkaloid lysergol and its derivatives against nalidixic acid-resistant Escherichia coli.  |  Maurya, A., et al. 2013. Chem Biol Drug Des. 81: 484-90. PMID: 23290001
  6. Application of quantitative structure-activity relationship models of 5-HT1A receptor binding to virtual screening identifies novel and potent 5-HT1A ligands.  |  Luo, M., et al. 2014. J Chem Inf Model. 54: 634-47. PMID: 24410373
  7. Identification of legal highs--ergot alkaloid patterns in two Argyreia nervosa products.  |  Paulke, A., et al. 2014. Forensic Sci Int. 242: 62-71. PMID: 25036782
  8. Total Syntheses of Pyroclavine, Festuclavine, Lysergol, and Isolysergol via a Catalytic Asymmetric Nitro-Michael Reaction.  |  Bhunia, S., et al. 2017. Chemistry. 23: 11234-11238. PMID: 28686308
  9. A Short Synthesis of Ergot Alkaloids and Evaluation of the 5-HT1/2 Receptor Selectivity of Lysergols and Isolysergols.  |  Tasker, NR. and Wipf, P. 2022. Org Lett. 24: 7255-7259. PMID: 35993579
  10. 5-Hydroxytryptamine (5-HT) contracts the guinea-pig isolated iliac artery via 5-HT1-like and 5-HT2 receptors.  |  Pertz, H. 1993. Naunyn Schmiedebergs Arch Pharmacol. 348: 558-65. PMID: 8133899
  11. Antibody binding of circulating ergot alkaloids in cattle grazing tall fescue.  |  Hill, NS., et al. 1994. Am J Vet Res. 55: 419-24. PMID: 8192270
  12. Naturally occurring clavines: antagonism/partial agonism at 5-HT2A receptors and antagonism at alpha 1-adrenoceptors in blood vessels.  |  Pertz, H. 1996. Planta Med. 62: 387-92. PMID: 8923801

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Lysergol, 100 mg

sc-229698
100 mg
$350.00