Date published: 2026-2-25

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Metaflumizone (CAS 139968-49-3)

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CAS Number:
139968-49-3
Molecular Weight:
506.40
Molecular Formula:
C24H16F6N4O2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Metaflumizone is a chemical compound that functions as a potent insecticide. Its mechanism of action involves targeting the nervous system of insects by binding to specific sites on the voltage-gated sodium channels. This binding disrupts the normal functioning of the channels, leading to prolonged and irreversible paralysis in the targeted insects. As a result, Metaflumizone effectively controls a wide range of insect pests, including lepidopteran, dipteran, and coleopteran species. Its mechanism of action at the molecular level involves blocking the sodium channels, preventing the influx of sodium ions and disrupting the generation and propagation of action potentials in the insect nervous system. This ultimately leads to the cessation of feeding and movement in the targeted pests, contributing to its efficacy as an insecticide in various experimental applications.


Metaflumizone (CAS 139968-49-3) References

  1. Determination of metaflumizone residues in cabbage and soil using ultra-performance liquid chromatography/ESI-MS/MS.  |  Dong, F., et al. 2009. J Sep Sci. 32: 3692-7. PMID: 19813227
  2. Baseline toxicity and field efficacy of metaflumizone on Colorado potato beetle (Coleoptera: Chrysomelidae).  |  Hitchner, EM., et al. 2012. J Econ Entomol. 105: 207-13. PMID: 22420273
  3. Degradation of metaflumizone in rice, water and soil under field conditions.  |  Li, C., et al. 2012. Ecotoxicol Environ Saf. 86: 73-8. PMID: 23079740
  4. Persistence of metaflumizone on cabbage (Brassica oleracea Linne) and soil, and its risk assessment.  |  Chatterjee, NS. and Gupta, S. 2013. Environ Monit Assess. 185: 6201-8. PMID: 23224645
  5. Baseline toxicity of metaflumizone and lack of cross resistance between indoxacarb and metaflumizone in diamondback moth (Lepidoptera: Plutellidae).  |  Khakame, SK., et al. 2013. J Econ Entomol. 106: 1423-9. PMID: 23865210
  6. Biochemical mechanisms for metaflumizone resistance in beet armyworm, Spodoptera exigua.  |  Tian, X., et al. 2014. Pestic Biochem Physiol. 113: 8-14. PMID: 25052521
  7. Fitness and inheritance of metaflumizone resistance in Plutella xylostella.  |  Shen, J., et al. 2017. Pestic Biochem Physiol. 139: 53-59. PMID: 28595922
  8. Metaflumizone inhibits the honeybee NaV 1 channel by targeting recovery from slow inactivation.  |  Gosselin-Badaroudine, P., et al. 2017. FEBS Lett. 591: 3842-3849. PMID: 29105054
  9. Resistance Risk Evaluated by Metaflumizone Selection and the Effects on Toxicities Over Other Insecticides in Spodoptera exigua (Lepidoptera: Noctuidae).  |  Sun, XX., et al. 2019. J Econ Entomol. 112: 2354-2361. PMID: 31219572
  10. Biochemical Mechanisms, Cross-resistance and Stability of Resistance to Metaflumizone in Plutella xylostella.  |  Shen, J., et al. 2020. Insects. 11: PMID: 32429053
  11. Method validation and residue analysis of methoxyfenozide and metaflumizone in Chinese broccoli under field conditions by liquid chromatography with tandem mass spectrometry.  |  Bi, Y., et al. 2021. J Sep Sci. 44: 3860-3869. PMID: 34384003
  12. Control efficacy and joint toxicity of metaflumizone mixed with chlorantraniliprole or indoxacarb against the fall armyworm, Spodoptera frugiperda.  |  Wu, YJ., et al. 2023. Pest Manag Sci. 79: 1094-1101. PMID: 36334007
  13. Dissipation pattern and safety assessment of fenazaquin and metaflumizone in butterbur (Petasites japonicus).  |  Sardar, SW., et al. 2023. J Environ Sci Health B. 58: 357-366. PMID: 37032589

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Metaflumizone, 100 mg

sc-228461
100 mg
$194.00