Molecular structure of Hederacoside C, CAS Number: 14216-03-6
Hederacoside C (CAS 14216-03-6)
Application:
Hederacoside C is a useful chemical that has been proposed to enhance lung cell function in vitro
CAS Number:
14216-03-6
Purity:
≥90%
Molecular Weight:
1221.38
Molecular Formula:
C59H96O26
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Hederacoside C is a saponin compound extensively studied for its biological activity in various non-clinical research applications. It is often a subject in plant biochemistry research, where scientists investigate its role as a chemical defense molecule in plants. In entomology, research involving Hederacoside C might focus on its potential effects on insect behavior and development, as it is naturally found in some plants that are resistant to insect predation. Additionally, it is utilized in studies concerning its modulating effects on membrane permeability, which is significant for understanding the interactions between plant-derived saponins and cell membranes. The compound is also of interest in environmental studies, where researchers examine the ecological role of saponins like Hederacoside C in plant ecosystems and their potential impact on soil and water quality.
Hederacoside C (CAS 14216-03-6) References
- An unusual case of death: suffocation caused by leaves of common ivy (Hedera helix). Detection of hederacoside C, alpha-hederin, and hederagenin by LC-EI/MS-MS. | Gaillard, Y., et al. 2003. J Anal Toxicol. 27: 257-62. PMID: 12820750
- Alpha-hederin, but not hederacoside C and hederagenin from Hedera helix, affects the binding behavior, dynamics, and regulation of beta 2-adrenergic receptors. | Sieben, A., et al. 2009. Biochemistry. 48: 3477-82. PMID: 19278262
- A Validated RP HPLC-PAD Method for the Determination of Hederacoside C in Ivy-Thyme Cough Syrup. | Khdair, A., et al. 2010. Int J Anal Chem. 2010: PMID: 20862201
- The effect of the whole extract of common ivy (Hedera helix) leaves and selected active substances on the motoric activity of rat isolated stomach strips. | Mendel, M., et al. 2011. J Ethnopharmacol. 134: 796-802. PMID: 21291987
- Pharmacokinetics of hederacoside C, an active ingredient in AG NPP709, in rats. | Kim, JM., et al. 2013. Xenobiotica. 43: 985-92. PMID: 23607546
- Determination of saponins and flavonoids in ivy leaf extracts using HPLC-DAD. | Yu, M., et al. 2015. J Chromatogr Sci. 53: 478-83. PMID: 24981979
- Complexation of phospholipids and cholesterol by triterpenic saponins in bulk and in monolayers. | Wojciechowski, K., et al. 2016. Biochim Biophys Acta. 1858: 363-73. PMID: 26654784
- Pharmacokinetic parameters of three active ingredients hederacoside C, hederacoside D, and ɑ-hederin in Hedera helix in rats. | Yu, M., et al. 2016. J Sep Sci. 39: 3292-301. PMID: 27377040
- An ultra-high-performance liquid chromatography-tandem mass spectrometric method for the determination of hederacoside C, a drug candidate for respiratory disorder, in rat plasma. | Rehman, SU., et al. 2016. J Pharm Biomed Anal. 129: 90-95. PMID: 27411171
- Revelation of the metabolic pathway of hederacoside C using an innovative data analysis strategy for dynamic multiclass biotransformation experiments. | Peeters, L., et al. 2019. J Chromatogr A. 1595: 240-247. PMID: 30833026
- Anti-inflammatory effects of Hederacoside-C on Staphylococcus aureus induced inflammation via TLRs and their downstream signal pathway in vivo and in vitro. | Akhtar, M., et al. 2019. Microb Pathog. 137: 103767. PMID: 31580956
- Hederacoside-C Inhibition of Staphylococcus aureus-Induced Mastitis via TLR2 & TLR4 and Their Downstream Signaling NF-κB and MAPKs Pathways In Vivo and In Vitro. | Akhtar, M., et al. 2020. Inflammation. 43: 579-594. PMID: 31845052
- Characterisation of hederacoside C metabolites using ultrahigh-performance liquid chromatography quadrupole Orbitrap mass spectrometry based on automatic fragment ion search. | Jiang, H., et al. 2020. Phytochem Anal. 31: 395-407. PMID: 31908080
- Hederacoside-C protects against AGEs-induced ECM degradation in mice chondrocytes. | Xu, HC., et al. 2020. Int Immunopharmacol. 84: 106579. PMID: 32413742
- Hederacoside C ameliorates colitis via restoring impaired intestinal barrier through moderating S100A9/MAPK and neutrophil recruitment inactivation. | Zha, ZX., et al. 2023. Acta Pharmacol Sin. 44: 105-119. PMID: 35732707
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Hederacoside C, 50 mg | sc-228271 | 50 mg | $178.00 |