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Farnesal (CAS 19317-11-4)

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Alternate Names:
3,7,11-Trimethyl-2,6,10-dodecatrienal
Application:
Farnesal is an unsaturated long chain aldehyde for proteomics research
CAS Number:
19317-11-4
Purity:
≥85%
Molecular Weight:
220.35
Molecular Formula:
C15H24O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Farnesal is an unsaturated long chain aldehyde for proteomics research. Farnesal is utilized as a reagent in the production of farnesylpyrophosphate analogues, which serve as bisubstrate inhibitors of protein farnesyltransferase. Additionally, farnesal exhibits antiparasitic properties.


Farnesal (CAS 19317-11-4) References

  1. Farnesol oxidation in insects: evidence that the biosynthesis of insect juvenile hormone is mediated by a specific alcohol oxidase.  |  Sperry, AE. and Sen, SE. 2001. Insect Biochem Mol Biol. 31: 171-8. PMID: 11164339
  2. Zeolite NaY-promoted cyclization of farnesal: a short route to nanaimoal.  |  Tsangarakis, C., et al. 2008. J Org Chem. 73: 2905-8. PMID: 18321121
  3. NADP+-dependent farnesol dehydrogenase, a corpora allata enzyme involved in juvenile hormone synthesis.  |  Mayoral, JG., et al. 2009. Proc Natl Acad Sci U S A. 106: 21091-6. PMID: 19940247
  4. Roles of rat and human aldo-keto reductases in metabolism of farnesol and geranylgeraniol.  |  Endo, S., et al. 2011. Chem Biol Interact. 191: 261-8. PMID: 21187079
  5. Aldehyde dehydrogenase 3 converts farnesal into farnesoic acid in the corpora allata of mosquitoes.  |  Rivera-Perez, C., et al. 2013. Insect Biochem Mol Biol. 43: 675-82. PMID: 23639754
  6. Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras-E-cadherin pathway.  |  Zhang, W., et al. 2014. Cancer Lett. 355: 273-80. PMID: 25304374
  7. Mevalonate-Farnesal Biosynthesis in Ticks: Comparative Synganglion Transcriptomics and a New Perspective.  |  Zhu, J., et al. 2016. PLoS One. 11: e0141084. PMID: 26959814
  8. Novel NAD+-Farnesal Dehydrogenase from Polygonum minus Leaves. Purification and Characterization of Enzyme in Juvenile Hormone III Biosynthetic Pathway in Plant.  |  Seman-Kamarulzaman, AF., et al. 2016. PLoS One. 11: e0161707. PMID: 27560927
  9. Draft Genome Sequence of Novosphingobium sp. Strain HII-3, a Bacterium Capable of Degrading the Cembranoid α(β)-2,7,11-Cembratriene-4,6-Diol to Farnesal.  |  Huang, S., et al. 2018. Genome Announc. 6: PMID: 29700133
  10. Antibacterial Performance of Terpenoids from the Australian Plant Eremophila lucida.  |  Biva, IJ., et al. 2019. Antibiotics (Basel). 8: PMID: 31108851
  11. Farnesal-loaded pH-sensitive polymeric micelles provided effective prevention and treatment on dental caries.  |  Yi, Y., et al. 2020. J Nanobiotechnology. 18: 89. PMID: 32527262
  12. Crystal structure and molecular characterization of NADP+-farnesol dehydrogenase from cotton bollworm, Helicoverpaarmigera.  |  Kumar, R., et al. 2022. Insect Biochem Mol Biol. 147: 103812. PMID: 35820537
  13. Transcriptomics-metabolomics joint analysis: New highlight into the triterpenoid saponin biosynthesis in quinoa (Chenopodium quinoa Willd.).  |  Zhao, Y., et al. 2022. Front Plant Sci. 13: 964558. PMID: 36340365
  14. Transcriptional profiling of the terpenoid biosynthesis pathway and in vitro tests reveal putative roles of linalool and farnesal in nectarine resistance against brown rot.  |  Balsells-Llauradó, M., et al. 2023. Plant Sci. 327: 111558. PMID: 36493930
  15. Formation of farnesal and 3-hydroxy-2,3-dihydrofarnesal from farnesol by protoplasts of Botryococcus braunii.  |  Inoue, H., et al. 1993. Biochem Biophys Res Commun. 196: 1401-5. PMID: 8250896

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Farnesal, 5 g

sc-228109
5 g
$183.00

Farnesal, 10 g

sc-228109A
10 g
$343.00

Farnesal, 50 g

sc-228109B
50 g
$1128.00