Date published: 2025-11-20

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Cyprodinil (CAS 121552-61-2)

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Alternate Names:
4-Cyclopropyl-6-methyl-N-phenylpyrimidin-2-amine
Application:
Cyprodinil is a novel broad spectrum anilinopyrimidine antifungal
CAS Number:
121552-61-2
Molecular Weight:
225.29
Molecular Formula:
C14H15N3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Cyprodinil is a synthetic chemical compound used primarily in scientific research for its role in inhibiting fungal growth through a distinct mode of action. It functions by interfering with the methionine biosynthesis pathway in fungi, specifically targeting the enzyme phenylalanine ammonia-lyase (PAL). This inhibition disrupts the synthesis of critical amino acids, leading to the cessation of fungal cell growth and division.Cyprodinil has been utilized to study its unique action mechanism among various fungal species. By understanding how cyprodinil affects methionine biosynthesis, researchers can gain insights into fungal metabolism and resistance mechanisms. This is particularly valuable in fields like agricultural science and mycology, where controlling fungal pathogens is essential for crop protection and storage. The use of cyprodinil in laboratory studies extends to genetic and molecular biology investigations, where it serves as a tool to explain the cellular processes underpinning fungal resilience and adaptation. Studies often focus on how fungal strains mutate or evolve resistance to inhibitors like cyprodinil, providing critical data for the development of new antifungal strategies or compounds with improved efficacy. Overall, cyprodinil′s role in scientific research highlights its importance in understanding fungal biology and developing methods to manage fungal-related issues in various environmental and agricultural settings.


Cyprodinil (CAS 121552-61-2) References

  1. Cyprodinil as an activator of aryl hydrocarbon receptor.  |  Fang, CC., et al. 2013. Toxicology. 304: 32-40. PMID: 23228475
  2. Photodegradation of cyprodinil under UV-visible irradiation - chemical and toxicological approaches.  |  Nicol, E., et al. 2016. Rapid Commun Mass Spectrom. 30: 2201-11. PMID: 27467462
  3. Molecular and biological characterization of Sclerotinia sclerotiorum resistant to the anilinopyrimidine fungicide cyprodinil.  |  Hou, YP., et al. 2018. Pestic Biochem Physiol. 146: 80-89. PMID: 29626996
  4. Complete genome sequence of the cyprodinil-degrading bacterium Acinetobacter johnsonii LXL_C1.  |  Wang, W., et al. 2019. Microb Pathog. 127: 246-249. PMID: 30496837
  5. Baseline Sensitivity of Didymella bryoniae to Cyprodinil and Fludioxonil and Field Efficacy of these Fungicides Against Isolates Resistant to Pyraclostrobin and Boscalid.  |  Keinath, AP. 2015. Plant Dis. 99: 815-822. PMID: 30699529
  6. DNA damage effect of cyprodinil and thiacloprid in adult zebrafish gills.  |  Toğay, VA., et al. 2021. Environ Sci Pollut Res Int. 28: 14482-14487. PMID: 33211291
  7. Long-term exposure to cyprodinil causes abnormal zebrafish aggressive and antipredator behavior through the hypothalamic-pituitary-interrenal axis.  |  Tang, C., et al. 2021. Aquat Toxicol. 241: 106002. PMID: 34717145
  8. Identification of Cyprodinil + Fludioxonil to Manage Soybean Red Crown Rot Using the Microplate-Based High-Throughput Screening and Pot Assay.  |  Wu, PH., et al. 2023. Plant Dis. PDIS08221976RE. PMID: 36302731
  9. Toxicity and ecological risk assessment for two AhR agonistic pesticides mepanipyrim and cyprodinil and their metabolites.  |  Shen, C., et al. 2023. Environ Sci Pollut Res Int. 30: 58944-58955. PMID: 37002518
  10. (-)-Epicatechin gallate ameliorates cyprodinil-induced cardiac developmental defects through inhibiting aryl hydrocarbon receptor in zebrafish.  |  Huang, D., et al. 2024. Birth Defects Res. 116: e2350. PMID: 38761027

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Cyprodinil, 250 mg

sc-227728
250 mg
$82.00