Molecular structure of (4-Hydroxyphenoxy)acetic acid, CAS Number: 1878-84-8
(4-Hydroxyphenoxy)acetic acid (CAS 1878-84-8)
CAS Number:
1878-84-8
Molecular Weight:
168.15
Molecular Formula:
C8H8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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A precursor of the amino acid L-dopa. (4-Hydroxyphenoxy)acetic acid is used in the design, synthesis and analysis of postulated transient intermediate and substrate analogues as inhibitors of 4-hyroxyphenylpyruvate dioxygenase. Shown to inhibit the activity of COX-2, which is involved in inflammation. Additionally, it is shown to modulate the expression of certain genes, such as those involved in cell growth and apoptosis.
(4-Hydroxyphenoxy)acetic acid (CAS 1878-84-8) References
- Differentiation of coronary smooth muscle cells to a cell cycle-arrested hypertrophic growth status by a synthetic non-toxic heparin-mimicking compound. | Schmidt, A., et al. 1999. Atherosclerosis. 147: 387-97. PMID: 10559525
- A synthetic heparin-mimicking polyanionic compound binds to the LDL receptor-related protein and inhibits vascular smooth muscle cell proliferation. | Benezra, M., et al. 2001. J Cell Biochem. 81: 114-27. PMID: 11180402
- Control of cell proliferation by heparan sulfate and heparin-binding growth factors. | Vlodavsky, I., et al. 1995. Thromb Haemost. 74: 534-40. PMID: 8578521
- Endogenous basic fibroblast growth factor displaced by heparin from the lumenal surface of human blood vessels is preferentially sequestered by injured regions of the vessel wall. | Medalion, B., et al. 1997. Circulation. 95: 1853-62. PMID: 9107173
- Modulation of fibroblast growth factor-2 receptor binding, dimerization, signaling, and angiogenic activity by a synthetic heparin-mimicking polyanionic compound. | Miao, HQ., et al. 1997. J Clin Invest. 99: 1565-75. PMID: 9120000
- Antiproliferative activity to glomerular mesangial cells and receptor binding of a heparin-mimicking polyaromatic anionic compound. | Katz, A., et al. 1997. J Am Soc Nephrol. 8: 1688-97. PMID: 9355071
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(4-Hydroxyphenoxy)acetic acid, 5 g | sc-226687 | 5 g | $65.00 |