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2-Mercaptophenol (CAS 1121-24-0)

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Alternate Names:
2-Hydroxythiophenol, 2-Sulfanylphenol
CAS Number:
1121-24-0
Molecular Weight:
126.18
Molecular Formula:
C6H6OS
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-Mercaptophenol is widely researched in the field of materials science and catalysis due to its thiol group, which provides a strong affinity for metal surfaces, facilitating the formation of self-assembled monolayers. This compound is also a key intermediate in the synthesis of more complex sulfur-containing organic molecules, which are useful in various industrial applications. Studies on 2-Mercaptophenol typically focus on enhancing its efficiency in binding with metals to improve the stability and electrical properties of metal-thiolate interfaces, which are for electronic and sensing devices. Additionally, the antioxidant properties of 2-Mercaptophenol are explored, particularly its ability to scavenge free radicals, which is relevant in the development of stabilizers for polymers and other materials. Research also assesses the environmental implications of using 2-Mercaptophenol, ensuring its applications are both effective and sustainable.


2-Mercaptophenol (CAS 1121-24-0) References

  1. Vanadium(IV) Complexes with Mixed O,S Donor Ligands. Syntheses, Structures, and Properties of the Anions Tris(2-mercapto-4-methylphenolato)vanadate(IV) and Bis(2-mercaptophenolato)oxovanadate(IV).  |  Klich, PR., et al. 1996. Inorg Chem. 35: 347-356. PMID: 11666215
  2. Modeling zinc enzyme inhibition with functional thiolate ligands.  |  Tekeste, T. and Vahrenkamp, H. 2006. Inorg Chem. 45: 10799-806. PMID: 17173439
  3. Speciation analysis of mercury in sediments, zoobenthos and river water samples by high-performance liquid chromatography hyphenated to atomic fluorescence spectrometry following preconcentration by solid phase extraction.  |  Margetínová, J., et al. 2008. Anal Chim Acta. 615: 115-23. PMID: 18442517
  4. Resolution via diastereomeric amides of enantiopure 1,4-benzoxathian-2- and 3-carboxylic acids and determination of their configuration.  |  Straniero, V., et al. 2022. Chirality. 34: 1053-1064. PMID: 35596548
  5. The in situ Preparation of 2‐Sulfidophenolate Ligands by Copper‐Catalyzed Oxygen Insertion into Thiophenolates; Crystal Structure of [PPh4] 2 [Mo2O5 (SC6H4O) 2]  |  Garner, C. D., Nicholson, J. R., & Clegg, W. 1984. Angewandte Chemie International Edition in English. 23(12): 972-973.
  6. Syntheses, structures, and properties of vanadium, cobalt, and nickel compounds with 2-mercaptophenol  |  Kang, B., Weng, L., Liu, H., Wu, D., Huang, L., Lu, C.,.. & Lu, J. 1990. Inorganic chemistry. 29(24): 4873-4877.
  7. Heterooctanuclear Cluster Complex Formation with Phosphine Participation: Synthesis, Structure, and Magnetic Properties of Co6Ru2 (mp) 10 (PBun3) 6 (H2mp= 2-Mercaptophenol, PBun3= Tri-n-butylphosphine)  |  Chen, Z. N., Li, W. J., Kang, B. S., Hong, M. C., Zhou, Z. Y., Mak, T. C.,.. & Liu, H. Q. 1997. Inorganic Chemistry. 36(2): 208-213.
  8. Palladium complexes with simultaneous O: S coordination, syntheses, structures and characterization of complexes with 2-mercaptophenol or 2-mercaptopyridine N-oxide  |  Shi, J. C., Wen, T. B., Zheng, Y., Zhong, S. J., Wu, D. X., Liu, Q. T.,.. & Mak, T. C. 1997. Polyhedron. 16(3): 369-375.
  9. Synthesis, Structure and Magnetic Properties of a Cyclic Heterotetranuclear Co3Fe Complex of 2‐Mercaptophenol (H2mp) with tri‐n‐Butylphosphine Participation  |  Chen, Z. N., Li, W. J., Rang, B. S., Zhang, H. X., Zhou, Z. Y., Mak, T. C.,.. & Liu, H. Q. 1998. Journal of the Chinese Chemical Society. 45(3): 367-373.
  10. Chemistry of 2-mercaptophenol (H2mp). Part iii. One dimensional arrays of binuclear anions of Mo (VI) linked by bis (2-hydroxyphenyl) disulfide via hydrogen bondings  |  Wang, X. J., Chen, Z. F., Kang, B. S., Liang, H., Liu, H. Q., Yu, K. B.,.. & Chen, Z. N. 1999. Polyhedron. 18(5): 647-655.
  11. Structural study of molybdenum (VI) complexes containing bidentate ligands: Synthesis, characterization and DFT calculations  |  Colorado-Peralta, R., Sanchez-Vazquez, M., Hernández-Ahuactzi, I. F., Sánchez-Ruiz, S. A., Contreras, R., Flores-Parra, A., & Castillo-Blum, S. E. 2012. Polyhedron. 48(1): 72-79.
  12. Synthesis, Characterization, and Evaluation of Antibacterial and Antioxidant Activities of Novel Benzoxazinones and Benzoxathiinones  |  Gholami, H. R., Asghari, S., & Mohseni, M. 2019. Journal of Heterocyclic Chemistry. 56(5): 1505-1513.
  13. Straightforward synthesis of benzoxazoles and benzothiazoles via photocatalytic radical cyclization of 2-substituted anilines with aldehydes  |  Le, H. A. N., Nguyen, L. H., Nguyen, Q. N. B., Nguyen, H. T., Nguyen, K. Q., & Tran, P. H. 2020. Catalysis Communications. 145: 106120.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Mercaptophenol, 5 g

sc-225442
5 g
$52.00