Date published: 2025-11-20

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2-Ethylhexyl diphenyl phosphate (CAS 1241-94-7)

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Application:
2-Ethylhexyl diphenyl phosphate is a plasticizer for resins
CAS Number:
1241-94-7
Purity:
≥90%
Molecular Weight:
362.40
Molecular Formula:
C20H27O4P
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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2-Ethylhexyl diphenyl phosphate (2-EHDP) is a plasticizer for resins. It is employed in a variety of industries, including plastics, coatings, paints, and adhesives. 2-Ethylhexyl diphenyl phosphate is a common additive to lubricating oils and greases, providing improved lubricity and corrosion protection. It is also used as a plasticizer and flame retardant in polymers and as a component of plasticizers in coatings, adhesives, and sealants.In addition, 2-Ethylhexyl diphenyl phosphate has been studied for its potential use as an alternative to other organophosphate esters, such as tricresyl phosphate, which are known to be toxic.


2-Ethylhexyl diphenyl phosphate (CAS 1241-94-7) References

  1. In vitro metabolism of 2-ethylhexyldiphenyl phosphate (EHDPHP) by human liver microsomes.  |  Ballesteros-Gómez, A., et al. 2015. Toxicol Lett. 232: 203-12. PMID: 25448284
  2. Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate.  |  Hu, W., et al. 2017. Environ Sci Technol. 51: 4061-4068. PMID: 28282128
  3. Organophosphate Ester, 2-Ethylhexyl Diphenyl Phosphate (EHDPP), Elicits Cytotoxic and Transcriptomic Effects in Chicken Embryonic Hepatocytes and Its Biotransformation Profile Compared to Humans.  |  Shen, J., et al. 2019. Environ Sci Technol. 53: 2151-2160. PMID: 30652482
  4. Adipogenic activity of 2-ethylhexyl diphenyl phosphate via peroxisome proliferator-activated receptor γ pathway.  |  Sun, W., et al. 2020. Sci Total Environ. 711: 134810. PMID: 31812418
  5. Perinatal exposure to 2-Ethylhexyl Diphenyl Phosphate (EHDPHP) affected the metabolic homeostasis of male mouse offspring: Unexpected findings help to explain dose- and diet- specific phenomena.  |  Yan, S., et al. 2020. J Hazard Mater. 388: 122034. PMID: 31951990
  6. 2-Ethylhexyl Diphenyl Phosphate and Its Hydroxylated Metabolites are Anti-androgenic and Cause Adverse Reproductive Outcomes in Male Japanese Medaka (Oryzias latipes).  |  Li, Y., et al. 2020. Environ Sci Technol. 54: 8919-8925. PMID: 32559385
  7. Maternal Transfer of 2-Ethylhexyl Diphenyl Phosphate Leads to Developmental Toxicity Possibly by Blocking the Retinoic Acid Receptor and Retinoic X Receptor in Japanese Medaka (Oryzias latipes).  |  Li, Y., et al. 2021. Environ Sci Technol. 55: 5056-5064. PMID: 33685123
  8. Isolation and identification of metabolites of 2-ethylhexyl diphenyl phosphate in rats.  |  Nishimaki-Mogami, T., et al. 1988. Arch Toxicol. 61: 259-64. PMID: 3377680
  9. Human CYP enzyme-activated clastogenicity of 2-ethylhexyl diphenyl phosphate (a flame retardant) in mammalian cells.  |  Chen, Z., et al. 2021. Environ Pollut. 285: 117527. PMID: 34380225
  10. Insights into the sex-dependent reproductive toxicity of 2-ethylhexyl diphenyl phosphate on zebrafish (Danio rerio).  |  Yang, R., et al. 2022. Environ Int. 158: 106928. PMID: 34638023
  11. Oxidative stress and ferroptosis involved in 2-ethylhexyl diphenyl phosphate -induced hepatotoxicity in chicken.  |  Yang, Y., et al. 2022. Chem Biol Interact. 368: 110216. PMID: 36228718
  12. First Insight into the Formation of In Vivo Transformation Products of 2-Ethylhexyl diphenyl phosphate in Zebrafish and Prediction of Their Potential Toxicities.  |  Yang, R., et al. 2023. Environ Sci Technol. 57: 451-462. PMID: 36515636
  13. Downregulation of miRNA-155-5p contributes to the adipogenic activity of 2-ethylhexyl diphenyl phosphate in 3T3-L1 preadipocytes.  |  Yue, J., et al. 2023. Toxicology. 487: 153452. PMID: 36764644
  14. Effects of 2-ethylhexyl diphenyl phosphate exposure on the glucolipid metabolism and cardiac developmental toxicity in larval zebrafish based on transcriptomic analysis.  |  Xu, S., et al. 2023. Comp Biochem Physiol C Toxicol Pharmacol. 267: 109578. PMID: 36822296
  15. First insight into the sex-dependent accumulation, tissue distribution and potential toxicities of 2-ethylhexyl diphenyl phosphate and its metabolites in adult zebrafish.  |  Yang, R., et al. 2023. J Hazard Mater. 452: 131299. PMID: 37027911

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-Ethylhexyl diphenyl phosphate, 25 g

sc-225350
25 g
$41.00