Molecular structure of Uvaol, CAS Number: 545-46-0
Uvaol (CAS 545-46-0)
Alternate Names:
Urs-12-ene-3,28-diol
CAS Number:
545-46-0
Molecular Weight:
442.72
Molecular Formula:
C30H50O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Uvaol is a naturally occurring phenolic compound present in numerous plants and fruits, and it belongs to the flavonoid class. Although the exact mechanism of action remains to be elucidated, Uvaol is thought to operate by regulating the activity of various enzymes implicated in inflammation and oxidative stress. Furthermore, Uvaol has demonstrated the ability to inhibit the growth of several cancer cell lines and to suppress the activity of enzymes associated with inflammation and oxidative stress.
Uvaol (CAS 545-46-0) References
- Determination of sterols, erythrodiol, uvaol and alkanols in olive oils using combined solid-phase extraction, high-performance liquid chromatographic and high-resolution gas chromatographic techniques. | Amelio, M., et al. 1992. J Chromatogr. 606: 179-85. PMID: 1430013
- Cardiotonic and antidysrhythmic effects of oleanolic and ursolic acids, methyl maslinate and uvaol. | Somova, LI., et al. 2004. Phytomedicine. 11: 121-9. PMID: 15070161
- A rapid method to determine sterol, erythrodiol, and uvaol concentrations in olive oil. | Mathison, B. and Holstege, D. 2013. J Agric Food Chem. 61: 4506-13. PMID: 23587059
- Role of Nitric Oxide and Hydrogen Sulfide in the Vasodilator Effect of Ursolic Acid and Uvaol from Black Cherry Prunus serotina Fruits. | Luna-Vázquez, FJ., et al. 2016. Molecules. 21: 78. PMID: 26771591
- Uvaol attenuates pleuritis and eosinophilic inflammation in ovalbumin-induced allergy in mice. | Agra, LC., et al. 2016. Eur J Pharmacol. 780: 232-42. PMID: 27038519
- Biomechanical and functional properties of trophoblast cells exposed to Group B Streptococcus in vitro and the beneficial effects of uvaol treatment. | Botelho, RM., et al. 2019. Biochim Biophys Acta Gen Subj. 1863: 1417-1428. PMID: 31254547
- Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages. | Du, SY., et al. 2020. Chin Med. 15: 43. PMID: 32411289
- Antiproliferative and Pro-Apoptotic Effect of Uvaol in Human Hepatocarcinoma HepG2 Cells by Affecting G0/G1 Cell Cycle Arrest, ROS Production and AKT/PI3K Signaling Pathway. | Bonel-Pérez, GC., et al. 2020. Molecules. 25: PMID: 32947962
- Uvaol Improves the Functioning of Fibroblasts and Endothelial Cells and Accelerates the Healing of Cutaneous Wounds in Mice. | Carmo, J., et al. 2020. Molecules. 25: PMID: 33126422
- Garland, Flower, and Petals via a Hierarchical Self-Assembly of Ursane-Type Triterpenoid Uvaol. | Ghorai, S. and Bag, BG. 2021. ACS Omega. 6: 20560-20568. PMID: 34396001
- Uvaol Prevents Group B Streptococcus-Induced Trophoblast Cells Inflammation and Possible Endothelial Dysfunction. | Silva, ALM., et al. 2021. Front Physiol. 12: 766382. PMID: 34925062
- Microbial transformation and inhibitory effect assessment of uvaol derivates against LPS and HMGB1 induced NO production in RAW264.7 macrophages. | Jiang, X., et al. 2022. Bioorg Med Chem Lett. 58: 128523. PMID: 34973341
- Persimmon Leaves: Nutritional, Pharmaceutical, and Industrial Potential-A Review. | Hossain, A. and Shahidi, F. 2023. Plants (Basel). 12: PMID: 36840285
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Uvaol, 25 mg | sc-224353 | 25 mg | $78.00 |