Date published: 2025-11-3

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(±)-Synephrine (CAS 94-07-5)

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Application:
(±)-Synephrine is an α-adrenergic receptor agonist
CAS Number:
94-07-5
Purity:
≥98%
Molecular Weight:
167.21
Molecular Formula:
C9H13NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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A α-adrenergic receptor agonist, vasoconstrictor.


(±)-Synephrine (CAS 94-07-5) References

  1. Hemodynamic effects of synephrine treatment in portal hypertensive rats.  |  Huang, YT., et al. 2001. Jpn J Pharmacol. 85: 183-8. PMID: 11286401
  2. Products containing bitter orange or synephrine: suspected cardiovascular adverse reactions.  |  Jordan, S., et al. 2004. CMAJ. 171: 993-4. PMID: 15497209
  3. Ischemic stroke associated with use of an ephedra-free dietary supplement containing synephrine.  |  Bouchard, NC., et al. 2005. Mayo Clin Proc. 80: 541-5. PMID: 15819293
  4. Sensitive determination of synephrine by flow-injection chemiluminescence.  |  Li, Q., et al. 2006. Luminescence. 21: 43-8. PMID: 16100748
  5. Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update.  |  Haaz, S., et al. 2006. Obes Rev. 7: 79-88. PMID: 16436104
  6. Ventricular fibrillation associated with use of synephrine containing dietary supplement.  |  Stephensen, TA. and Sarlay, R. 2009. Mil Med. 174: 1313-9. PMID: 20055074
  7. Effects of synephrine and beta-phenethylamine on human alpha-adrenoceptor subtypes.  |  Ma, G., et al. 2010. Planta Med. 76: 981-6. PMID: 20217639
  8. Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium.  |  Mercader, J., et al. 2011. J Physiol Biochem. 67: 443-52. PMID: 21336650
  9. Activities of octopamine and synephrine stereoisomers on alpha-adrenoceptors.  |  Brown, CM., et al. 1988. Br J Pharmacol. 93: 417-29. PMID: 2833972
  10. Activities of octopamine and synephrine stereoisomers on octopaminergic receptor subtypes in locust skeletal muscle.  |  Evans, PD., et al. 1988. J Pharm Pharmacol. 40: 855-61. PMID: 2907578
  11. Preparative enantioseparation of synephrine by conventional and pH-zone-refining counter-current chromatography.  |  Zhang, Y., et al. 2018. J Chromatogr A. 1575: 122-127. PMID: 30224280
  12. Co-Existence of Hypertensive and Anti-Hypertensive Constituents, Synephrine, and Nobiletin in Citrus unshiu Peel.  |  Kim, JJ., et al. 2019. Molecules. 24: PMID: 30934724
  13. Differential mechanisms of action of the trace amines octopamine, synephrine and tyramine on the porcine coronary and mesenteric artery.  |  Koh, AHW., et al. 2019. Sci Rep. 9: 10925. PMID: 31358768
  14. [Synephrine in dietary supplements and specialized foodstuffs: biological activity, safety and methods of analysis].  |  Perova, IB., et al. 2021. Vopr Pitan. 90: 101-113. PMID: 35032130
  15. The unique nature of the serine interactions for alpha 1-adrenergic receptor agonist binding and activation.  |  Hwa, J. and Perez, DM. 1996. J Biol Chem. 271: 6322-7. PMID: 8626427

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(±)-Synephrine, 25 g

sc-220182
25 g
$245.00