Date published: 2025-11-20

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Precocene ii (CAS 644-06-4)

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Alternate Names:
6,7-Dimethoxy-2,2-dimethylchromene; 6,7-Dimethoxy-2,2-dimethylchromene; Ageratochromene
Application:
Precocene ii is a useful insecticidal reagent for proteomics research
CAS Number:
644-06-4
Purity:
98%
Molecular Weight:
220.26
Molecular Formula:
C13H16O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Precocene ii contains anti-juvenile hormones that are found in plants. This ends up inducing reversible sterilization and precocious metamorphosis in insects by suppressing the function of the corpora allata gland. Juvenile hormones is for regulating development, reproduction, and metamorphosis in insects. Researchers use precocene II to study hormonal control mechanisms in insects, exploring how hormonal imbalances influence insect development and behavior. It helps in understanding the hormonal regulation pathways and the potential for targeting these pathways in pest management strategies.


Precocene ii (CAS 644-06-4) References

  1. Perturbed turnover of microtubule-based nutritive tubes in ovarioles of virgin and precocene-treated Dysdercus fasciatus.  |  Stebbings, H. 2002. Arch Insect Biochem Physiol. 50: 31-40. PMID: 11948973
  2. Identification and action of juvenile hormone III from sexually mature alate females of the red imported fire ant, Solenopsis invicta.  |  Burns, SN., et al. 2002. J Insect Physiol. 48: 357-365. PMID: 12770110
  3. Sensitive periods for wing development and precocious metamorphosis after precocene treatment of the brown planthopper, Nilaparvata lugens.  |  Bertuso, AG., et al. 2002. J Insect Physiol. 48: 221-229. PMID: 12770122
  4. Effect of precocene on development of ovarian follicles in flesh fly, Sarcophaga ruficornis F.  |  Kumar, K. and Khan, IA. 2004. Indian J Exp Biol. 42: 74-80. PMID: 15274485
  5. Synthesis and insect antifeedant activity of precocene derivatives with lactone moiety.  |  Szczepanik, M., et al. 2005. J Agric Food Chem. 53: 5905-10. PMID: 16028972
  6. [Influence of precocene II on the sensory system of antennae and mouthparts in larvae of the fruit tree tortricid Archips podana Scop. (Lepidoptera: Tortricidae)].  |  Triseleva, TA. 2007. Izv Akad Nauk Ser Biol. 557-62. PMID: 18038622
  7. Acaricidal properties of the essential oil and precocene II obtained from Calea serrata (Asteraceae) on the cattle tick Rhipicephalus (Boophilus) microplus (Acari: Ixodidae).  |  Ribeiro, VL., et al. 2011. Vet Parasitol. 179: 195-8. PMID: 21402447
  8. Sensitivity of last larval stadium of Chrysomya megacephala (Fabricius) to anti-allatin ageratochromene Precocene II.  |  Singh, S. and Kumar, K. 2011. Indian J Exp Biol. 49: 600-8. PMID: 21870428
  9. Correlation of ATP citrate lyase and acetyl CoA levels with trichothecene production in Fusarium graminearum.  |  Sakamoto, N., et al. 2013. Toxins (Basel). 5: 2258-69. PMID: 24284828
  10. Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum.  |  Furukawa, T., et al. 2015. PLoS One. 10: e0135031. PMID: 26248339
  11. Search for aflatoxin and trichothecene production inhibitors and analysis of their modes of action.  |  Sakuda, S., et al. 2016. Biosci Biotechnol Biochem. 80: 43-54. PMID: 26376763
  12. Anti-neuropathic pain mechanistic study of A. conyzoides essential oil, Precocene II, Caryophyllene, or Longifolene as single agent and in combination with pregabalin.  |  Sukmawan, YP., et al. 2022. CNS Neurol Disord Drug Targets.. PMID: 35440325
  13. The Synthesis, Fungicidal Activity, and in Silico Study of Alkoxy Analogues of Natural Precocenes I, II, and III.  |  Ramadan, KMA., et al. 2022. Molecules. 27: PMID: 36364004
  14. Metabolic fate of the hepatotoxic anti-juvenile hormone precocene II in the rat.  |  Grossman, SJ. and Hsia, MT. 1982. Toxicology. 25: 293-8. PMID: 7157406

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Precocene ii, 250 mg

sc-219640
250 mg
$301.00

Precocene ii, 500 mg

sc-219640A
500 mg
$490.00