Molecular structure of Naringenin, CAS Number: 480-41-1
Naringenin (CAS 480-41-1)
See product citations (11)
Alternate Names:
2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one; (R,S)-Naringenin; (±)-5,7,4-Trihydroxyflavanone; 5,7,4-Trihydroxyflavanone
Application:
Naringenin is the aglucon of naringin
CAS Number:
480-41-1
Purity:
98%
Molecular Weight:
272.25
Molecular Formula:
C15H12O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Naringenin is a flavonoid compound that has captured the interest of researchers due to its involvement in various biological mechanisms and potential applications in biotechnological fields. In botanical studies, naringenin is recognized for its role in plant defense and its contribution to the pigmentation and flavor profile of fruits. Biochemically, research on naringenin includes investigating its influence on enzyme activity, particularly those involved in antioxidant pathways, where it is known to affect signaling cascades and gene expression. Its interactions with microbial populations are also a subject of study, providing insights into the symbiotic and defensive relationships between plants and microbes.
Naringenin (CAS 480-41-1) References
- Apolipoprotein B-dependent hepatitis C virus secretion is inhibited by the grapefruit flavonoid naringenin. | Nahmias, Y., et al. 2008. Hepatology. 47: 1437-45. PMID: 18393287
- Naringenin inhibits the assembly and long-term production of infectious hepatitis C virus particles through a PPAR-mediated mechanism. | Goldwasser, J., et al. 2011. J Hepatol. 55: 963-71. PMID: 21354229
- Naringenin attenuates non-alcoholic fatty liver disease by down-regulating the NLRP3/NF-κB pathway in mice. | Wang, Q., et al. 2020. Br J Pharmacol. 177: 1806-1821. PMID: 31758699
- Naringenin alleviates cognition deficits in high-fat diet-fed SAMP8 mice. | Zhou, T., et al. 2020. J Food Biochem. 44: e13375. PMID: 32677738
- Naringenin alleviates nonalcoholic steatohepatitis in middle-aged Apoe-/-mice: role of SIRT1. | Hua, YQ., et al. 2021. Phytomedicine. 81: 153412. PMID: 33234364
- The Effects of Naringenin on miRNA-mRNA Profiles in HepaRG Cells. | Fan, W., et al. 2021. Int J Mol Sci. 22: PMID: 33669020
- Naringenin promotes SDF-1/CXCR4 signaling pathway in BMSCs osteogenic differentiation. | Wang, Y., et al. 2021. Folia Histochem Cytobiol. 59: 66-73. PMID: 33704767
- Naringenin mitigates behavioral alterations and provides neuroprotection against 3-nitropropinoic acid-induced Huntington's disease like symptoms in rats. | Salman, M., et al. 2022. Nutr Neurosci. 25: 1898-1908. PMID: 33856270
- Structure, isomerization and dimerization processes of naringenin flavonoids. | González Moreno, A., et al. 2021. Phys Chem Chem Phys. 23: 18068-18077. PMID: 34388230
- Anticancer Potential of Naringenin, Biosynthesis, Molecular Target, and Structural Perspectives. | Prakash, O., et al. 2022. Mini Rev Med Chem. 22: 758-769. PMID: 34517796
- Naringenin affords protection against lipopolysaccharide/D-galactosamine-induced acute liver failure: Role of autophagy. | Ahmedy, OA., et al. 2022. Arch Biochem Biophys. 717: 109121. PMID: 35065059
- Naringenin Protects against Hypertension by Regulating Lipid Disorder and Oxidative Stress in a Rat Model. | Liu, H., et al. 2022. Kidney Blood Press Res. 47: 423-432. PMID: 35354142
- Naringenin activates beige adipocyte browning in high fat diet-fed C57BL/6 mice by shaping the gut microbiota. | Zhang, S., et al. 2022. Food Funct. 13: 9918-9930. PMID: 36053256
- Naringenin confers defence against Phytophthora nicotianae through antimicrobial activity and induction of pathogen resistance in tobacco. | Sun, M., et al. 2022. Mol Plant Pathol. 23: 1737-1750. PMID: 36094814
- Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man. | Fuhr, U., et al. 1993. Br J Clin Pharmacol. 35: 431-6. PMID: 8485024
Inhibitor of:
γ-synuclein, κ-casein, 5 alpha-Reductase 2, Angptl4, ATP-binding cassette (ABC) transporter, BSEP, c-Jun, CaMK2N2, Carbonyl reductase 3, CBARA1 (MICU1), CCDC109A, Ces1a, CHST5, CHST6, CXorf49B, CYP3A, CYP4A12A, Cyp4f15, CYP7A1, DDX50, EG574081, Esp18, Factor H, FOXD4L2-6, GAL3ST3, galectin-3, GSTT2, Hep A sAg, HMGCR, HPV16 E1, HSL, HYAL3, LBP1, MASP-2, Measles NP, MOV10, NTCP, Nucling, OATP-H, Oatp3, Olfr1084, Olfr1288, Olfr981, PATE3, Perilipin, Prostein, Psg23, Psg25, Psg26, Psg27, Psg28, Psg29, PSGL-1, RDH8, resistin-like γ, RFT1, Rhox6, Rhox7, SGLT-3, SLC10A6, SPRR2, SR140, SREB1, Staphylococcus aureus TSST-1, Sulfotransferase (SULT1), SULT1A3, SULT1B1, SULT2A2, SULT2B10, SULT5A1, SV40 T Ag, Svs1, Svs2, Svs6, syncytin-A, T2R134, T2R17, T2R37, TAAR3, TAAR7A, Tas2r102, Tas2r114, Tas2r140, Tas2r143, TEX24, TIA-1, TMPRSSs8, TRP1, TRPV6, UGT1A6B, UGT1A7, UGT2A1, UGT2A2, UGT2B36, UGT2B37, UGT2B38, UGT2B4, UGT2B5, UGT8, UGTREL1, V1RC2, V1RC21, V1RC26, V1rc29, V1rc7, V1RF4, V1RG11, Vgl-3, and ZNF737.Activator of:
αENaC, 17-β Estradiol 6, AATK, AdipoR2, ALDH2, BBS9, BChE, Bclp2, C1qL4, C21orf70, C22orf15, C6orf10, carbonyl reductase 2, Caveolin-1, CCDC66, CCDC87, CES7, cryptdin 3, Cyclin D1, cyclin J, CYP2B1, CYP2B2, CYP2B23, CYP2D11, CYP2T4, Cyp3a41a, Cyp3a57, CYP4F12, CYP4F8, DNA pol ε 4, DNAH2, DnaJC25, DNAJC25-GNG10, DNAL4, Embigin, GALC, GRP 78, Hsp104, HUGT2, IGF-IRβ, IL-1R8, IL-8RA, Klkb1, MAGE-D2, MASGP-BP, MaxiKα, MB67_CAR1/2, MBIP, MrgA5, NaDC-1, NALP9A, NPC1, NTR2, OAT6, OATP-B, OATP1, OR11H6, OR2M5, OR4N2, OTTMUSG00000018259, Pellino 2, PGRP-L, PLD6, Polycystin-1, PSMD5, Rab 28, resistin, ROGDI, Ros, RTCD1, Selenoprotein S, Siglec-G, Smad4, sodium/potassium-ATPase α1, SPLUNC2, SULT2A4, SULT2A5, SULT2A7, TIMP-2, TRPM4, UCP4, UGT1A6, UGT2B, UGT2B28, UGT2B4, UGT3A1, USP29, VPS33B, ZNF434, and ZNF484.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Naringenin, 25 g | sc-219338 | 25 g | $245.00 |