Aloe-emodin (CAS 481-72-1)
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Aloe-emodin, a natural compound found in the leaves of the Aloe vera plant, has garnered considerable attention due to its diverse properties. As a polyphenol compound, it exhibits a broad range of biological activities, including anti-inflammatory, antioxidant, anti-tumor, and anti-microbial effects. Extensive research has focused on exploring the potential benefits of Aloe-emodin. The precise mechanism of action of Aloe-emodin is not yet fully elucidated, although it is believed to involve the inhibition of various enzymes and receptors, as well as its interaction with DNA. In vitro studies have been conducted to investigate its effects on different cell lines. These studies have revealed promising findings, suggesting that Aloe-emodin holds potential for combating inflammation, oxidative stress, and cancer.
Aloe-emodin (CAS 481-72-1) References
- Aloe-emodin induces apoptosis in human oral squamous cell carcinoma SCC15 cells. | Li, Q., et al. 2018. BMC Complement Altern Med. 18: 296. PMID: 30404637
- Aloe-emodin, a hydroxyanthracene derivative, is not genotoxic in an in vivo comet test. | Galli, CL., et al. 2021. Regul Toxicol Pharmacol. 124: 104967. PMID: 34062205
- Aloe-emodin-mediated antimicrobial photodynamic therapy against dermatophytosis caused by Trichophyton rubrum. | Ma, W., et al. 2022. Microb Biotechnol. 15: 499-512. PMID: 34165875
- Aloe-emodin prevents nerve injury and neuroinflammation caused by ischemic stroke via the PI3K/AKT/mTOR and NF-κB pathway. | Xian, M., et al. 2021. Food Funct. 12: 8056-8067. PMID: 34286782
- Abscisic acid and aloe-emodin against NS2B-NS3A protease of Japanese encephalitis virus. | Bhimaneni, S. and Kumar, A. 2022. Environ Sci Pollut Res Int. 29: 8759-8766. PMID: 34490576
- Aloe-emodin derivative produces anti-atherosclerosis effect by reinforcing AMBRA1-mediated endothelial autophagy. | Tang, X., et al. 2022. Eur J Pharmacol. 916: 174641. PMID: 34800465
- Development of a novel anti-liver fibrosis formula with luteolin, licochalcone A, aloe-emodin and acacetin by network pharmacology and transcriptomics analysis. | Zhou, Y., et al. 2021. Pharm Biol. 59: 1594-1606. PMID: 34808067
- Inhibition of CYP3A4 enhances aloe-emodin induced hepatocyte injury. | Hu, YH., et al. 2022. Toxicol In Vitro. 79: 105276. PMID: 34875353
- Aloe-emodin inhibits the proliferation, migration, and invasion of melanoma cells via inactivation of the Wnt/beta-catenin signaling pathway. | Du, M., et al. 2021. Ann Transl Med. 9: 1722. PMID: 35071416
- Cerebroprotective effect of Aloe Emodin: In silico and in vivo studies. | Pasala, PK., et al. 2022. Saudi J Biol Sci. 29: 998-1005. PMID: 35197769
- Aloe-Emodin Ameliorates Diabetic Nephropathy by Targeting Interferon Regulatory Factor 4. | Lu, L. and Li, Y. 2022. Evid Based Complement Alternat Med. 2022: 2421624. PMID: 35518350
- Aloe-Emodin Induces Mitochondrial Dysfunction and Pyroptosis by Activation of the Caspase-9/3/Gasdermin E Axis in HeLa Cells. | Li, T., et al. 2022. Front Pharmacol. 13: 854526. PMID: 35662735
- The Comparison of the Efficiency of Emodin and Aloe-Emodin in Photodynamic Therapy. | Nowak-Perlak, M., et al. 2022. Int J Mol Sci. 23: PMID: 35682955
- Peptide-Mediated Targeted Delivery of Aloe-Emodin as Anticancer Drug. | Stringaro, A., et al. 2022. Molecules. 27: PMID: 35889487
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Aloe-emodin, 100 mg | sc-217613 | 100 mg | $158.00 |