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Petroselinic acid (CAS 593-39-5)

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Alternate Names:
5-Heptadecylene-1-carboxylic acid
Application:
Petroselinic acid is a monounsaturated omega-12 fatty acid
CAS Number:
593-39-5
Molecular Weight:
282.46
Molecular Formula:
C18H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Petroselinic acid is a monounsaturated omega-12 fatty acid found naturally in plant and animal oils and fats. Petroselinic acid act on several pathways, including the PPAR-γ pathway, the NF-κB pathway, and the AMPK pathway. The PPAR-γ pathway is involved in the regulation of inflammation, while the NF-κB pathway is involved in the regulation of oxidative stress. The AMPK pathway is involved in the regulation of insulin sensitivity.


Petroselinic acid (CAS 593-39-5) References

  1. An unusual seed-specific 3-ketoacyl-ACP synthase associated with the biosynthesis of petroselinic acid in coriander.  |  Mekhedov, S., et al. 2001. Plant Mol Biol. 47: 507-18. PMID: 11669576
  2. Metabolic Evidence for the Involvement of a [delta]4-Palmitoyl-Acyl Carrier Protein Desaturase in Petroselinic Acid Synthesis in Coriander Endosperm and Transgenic Tobacco Cells.  |  Cahoon, EB. and Ohlrogge, JB. 1994. Plant Physiol. 104: 827-837. PMID: 12232129
  3. Expression of a coriander desaturase results in petroselinic acid production in transgenic tobacco.  |  Cahoon, EB., et al. 1992. Proc Natl Acad Sci U S A. 89: 11184-8. PMID: 1454797
  4. Geranium sanguineum (Geraniaceae) seed oil: a new source of petroselinic and vernolic acid.  |  Tsevegsuren, N., et al. 2004. Lipids. 39: 571-6. PMID: 15554157
  5. Evaluation of the impact of dietary petroselinic acid on the growth performance, fatty acid composition, and efficacy of long chain-polyunsaturated fatty acid biosynthesis of farmed Nile tilapia.  |  Teoh, CY. and Ng, WK. 2013. J Agric Food Chem. 61: 6056-68. PMID: 23718861
  6. Petroselinic acid purification and its use for the fermentation of new sophorolipids.  |  Delbeke, EIP., et al. 2016. AMB Express. 6: 28. PMID: 27033544
  7. Characterization of French Coriander Oil as Source of Petroselinic Acid.  |  Uitterhaegen, E., et al. 2016. Molecules. 21: PMID: 27617992
  8. Transcriptome Analysis Reveals Candidate Genes for Petroselinic Acid Biosynthesis in Fruits of Coriandrum sativum L.  |  Yang, Z., et al. 2020. J Agric Food Chem. 68: 5507-5520. PMID: 32320606
  9. Fatty acid composition and oil content during coriander fruit development.  |  Nguyen, QH., et al. 2020. Food Chem. 326: 127034. PMID: 32438233
  10. Preoperative fasting confers protection against intestinal ischaemia/reperfusion injury by modulating gut microbiota and their metabolites in a mouse model.  |  Huang, W., et al. 2022. Br J Anaesth. 128: 501-512. PMID: 34930601
  11. Inhibition of Staphylococcus aureus Biofilm Formation and Virulence Factor Production by Petroselinic Acid and Other Unsaturated C18 Fatty Acids.  |  Lee, JH., et al. 2022. Microbiol Spectr. 10: e0133022. PMID: 35647620
  12. Dual Inhibitory Activity of Petroselinic Acid Enriched in Fennel Against Porphyromonas gingivalis.  |  Yoshino, N., et al. 2022. Front Microbiol. 13: 816047. PMID: 35663901
  13. Petroselinic acid biosynthesis and production in transgenic plants.  |  Cahoon, EB., et al. 1994. Prog Lipid Res. 33: 155-63. PMID: 8190735

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Petroselinic acid, 100 mg

sc-215696
100 mg
$150.00