Lumichrome (CAS 1086-80-2)

Lumichrome is a derivative of riboflavin (vitamin B2) and is known for its distinctive structural and photophysical properties. It is a non-fluorescent compound that absorbs in the UV-A and blue light regions, making it an interesting subject in the study of photochemistry and photobiology. Lumichrome is characterized by the removal of the ribityl side chain from riboflavin, which significantly alters its chemical behavior compared to its parent compound. The primary mechanism of action of lumichrome involves its role as a photosensitizer. It can absorb light and transfer energy to other molecules, leading to the generation of reactive oxygen species (ROS) or singlet oxygen under specific conditions. This property is used in research to understand the effects of light-induced oxidative stress on biological systems and the role of singlet oxygen in various photochemical processes. In scientific research, lumichrome has been used to study the interactions between light and living organisms, particularly in understanding how light influences cellular and molecular processes. Its ability to absorb light and participate in energy transfer makes it a useful probe in studies of photoreceptor behavior and the mechanisms underlying phototaxis and phototropism in plants and microorganisms. Furthermore, lumichrome has been investigated for its effects on metabolic processes. Studies have shown that lumichrome can influence the cellular respiration rate and mitochondrial function. By modulating the activity of certain key enzymes in the respiratory chain, lumichrome can alter the production of ATP, providing insights into how cells manage energy production and consumption in response to environmental changes.