Aristolochic acid sodium salt (CAS 10190-99-5)

Aristolochic acid 1 sodium salt is a compound that functions as a potent inhibitor of DNA repair enzymes, those involved in nucleotide excision repair. Aristolochic Acid 1 Sodium Salt exerts its mechanism of action by forming covalent adducts with DNA, leading to the formation of DNA adducts that can cause mutations and DNA damage. By interfering with the repair of DNA damage, aristolochic acid 1 sodium salt can contribute to the accumulation of genetic mutations and genomic instability. Aristolochic Acid 1 Sodium Salt may have a high affinity for DNA, leading to the formation of DNA adducts that can disrupt the normal functioning of the genetic material. In experimental applications, aristolochic acid 1 sodium salt is used to study the mechanisms of DNA damage and repair, as well as to investigate its potential role in the development of genetic dispasitions. Its ability to interfere with DNA repair processes may be a function for understanding the molecular mechanisms underlying genomic instability and mutagenesis.