Date published: 2025-10-19

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Ammonium fluoride (CAS 12125-01-8)

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Application:
Ammonium fluoride is a probe used for solid-state lasers as well as for photoluminescence and magnetic characteristics
CAS Number:
12125-01-8
Purity:
≥96%
Molecular Weight:
37.04
Molecular Formula:
NH4F
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Ammonium fluoride is an inorganic compound consisting of ammonium and fluoride ions. It is a solid substance with a white crystalline structure, emitting a strong odor and being insoluble in water. This compound finds diverse applications, particularly in organic compound synthesis, serving as a reagent during laboratory experiments. Its main function involves acting as an inhibitor of enzymes. By binding to specific enzymes like proteases and phosphatases, it effectively hinders their activity. Furthermore, ammonium fluoride has demonstrated its capability to impede the function of DNA-binding proteins, such as transcription factors, and influence the expression of particular genes. Moreover, it has been observed to modulate the functioning of specific intracellular signaling pathways.


Ammonium fluoride (CAS 12125-01-8) References

  1. Determination of copper in ammonium fluoride solutions by extraction and atomic-absorption spectrophotometry.  |  Briska, M. and Hoffmeister, W. 1973. Talanta. 20: 895-7. PMID: 18961361
  2. Ammonium fluoride as a mobile phase additive in aqueous normal phase chromatography.  |  Pesek, JJ. and Matyska, MT. 2015. J Chromatogr A. 1401: 69-74. PMID: 26008598
  3. Structural and Ionic Transport Properties of Protonic Conducting Solid Biopolymer Electrolytes Based on Carboxymethyl Cellulose Doped with Ammonium Fluoride.  |  Ramlli, MA. and Isa, MI. 2016. J Phys Chem B. 120: 11567-11573. PMID: 27723333
  4. Ammonium Fluoride Mediated Synthesis of Anhydrous Metal Fluoride-Mesoporous Carbon Nanocomposites for High-Performance Lithium Ion Battery Cathodes.  |  Chun, J., et al. 2016. ACS Appl Mater Interfaces. 8: 35180-35190. PMID: 27754647
  5. Calcium carbide catalytically activated with tetra-n-butyl ammonium fluoride for Sonogashira cross coupling reactions.  |  Hosseini, A., et al. 2017. Org Biomol Chem. 15: 6800-6807. PMID: 28770930
  6. Antibacterial Effect of Silver Diammine Fluoride on Cariogenic Organisms.  |  Lou, Y., et al. 2018. J Contemp Dent Pract. 19: 591-598. PMID: 29807972
  7. Ammonium Fluoride Passivation of CdZnTeSe Sensors for Applications in Nuclear Detection and Medical Imaging.  |  Egarievwe, SU., et al. 2019. Sensors (Basel). 19: PMID: 31349605
  8. A rapid ammonium fluoride method to determine the oxygen isotope ratio of available phosphorus in tropical soils.  |  Pfahler, V., et al. 2020. Rapid Commun Mass Spectrom. 34: e8647. PMID: 31671472
  9. Ammonium Fluoride as Suitable Additive for HILIC-Based LC-HRMS Metabolomics.  |  Narduzzi, L., et al. 2019. Metabolites. 9: PMID: 31783638
  10. Ammonium tantalum oxide fluorides: new features of dynamic disorder.  |  Udovenko, AA. and Laptash, NM. 2019. Acta Crystallogr B Struct Sci Cryst Eng Mater. 75: 1164-1173. PMID: 32830696
  11. Effect of ammonium fluoride doping on the ice III to ice IX phase transition.  |  Sharif, Z., et al. 2021. J Chem Phys. 154: 114502. PMID: 33752367
  12. Ammonium fluoride's analogy to ice: Possibilities and limitations.  |  Conway, LJ., et al. 2021. J Chem Phys. 154: 204501. PMID: 34241159
  13. Comparison of the phase transitions of high-pressure phases of ammonium fluoride and ice at ambient pressure.  |  Sharif, Z. and Salzmann, CG. 2022. J Chem Phys. 156: 014502. PMID: 34998346
  14. Multi-steroid profiling by UHPLC-MS/MS with post-column infusion of ammonium fluoride.  |  Schiffer, L., et al. 2022. J Chromatogr B Analyt Technol Biomed Life Sci. 1209: 123413. PMID: 35988498

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Ammonium fluoride, 100 g

sc-210806
100 g
$97.00

Ammonium fluoride, 500 g

sc-210806A
500 g
$229.00