Molecular structure of 5,7-Dimethoxycoumarin, CAS Number: 487-06-9
5,7-Dimethoxycoumarin (CAS 487-06-9)
Alternate Names:
Citropten; Limettin
Application:
5,7-Dimethoxycoumarin is a derivitized coumarin compound
CAS Number:
487-06-9
Molecular Weight:
206.19
Molecular Formula:
C11H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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5,7-Dimethoxycoumarin is a naturally occurring compound that can be found in citrus fruits. Researchers have conducted in vitro studies to investigate the mechanisms of action of this compound. It has been found to act as an inhibitor of enzymes involved in the inflammatory response, including cyclooxygenase-2 and 5-lipoxygenase. Moreover, 5,7-Dimethoxycoumarin has demonstrated inhibitory effects on enzymes associated with cancer cell growth and proliferation, such as telomerase and matrix metalloproteinases.
5,7-Dimethoxycoumarin (CAS 487-06-9) References
- Cell cycle arrest and differentiation induction by 5,7-dimethoxycoumarin in melanoma cell lines. | Alesiani, D., et al. 2008. Int J Oncol. 32: 425-34. PMID: 18202765
- Inhibition of Mek 1/2 kinase activity and stimulation of melanogenesis by 5,7-dimethoxycoumarin treatment of melanoma cells. | Alesiani, D., et al. 2009. Int J Oncol. 34: 1727-35. PMID: 19424591
- Isolation And Structure Elucidation Of 5,7-disubstituted Simple Coumarins In The Fruits Of Heracleum Mantegazzianum. | Glowniak, K., et al. 2000. Pharm Biol. 38: 308-12. PMID: 21214482
- Chemical composition of hexane extract of Citrus aurantifolia and anti-Mycobacterium tuberculosis activity of some of its constituents. | Sandoval-Montemayor, NE., et al. 2012. Molecules. 17: 11173-84. PMID: 22992784
- Evaluation of melanogenesis in A-375 melanoma cells treated with 5,7-dimethoxycoumarin and valproic acid. | Chodurek, E., et al. 2012. Cell Mol Biol Lett. 17: 616-32. PMID: 23001511
- Analysis of fluorescence quenching of coumarin derivatives by 4-hydroxy-TEMPO in aqueous solution. | Żamojć, K., et al. 2014. J Fluoresc. 24: 713-8. PMID: 24337873
- Coumarins from Edgeworthia chrysantha. | Li, XN., et al. 2014. Molecules. 19: 2042-8. PMID: 24531219
- Antiproliferative effect of valproic acid and 5,7-dimethoxycoumarin against A2058 human melanoma cells. | Wolny, D., et al. 2014. Acta Pol Pharm. 71: 1056-9. PMID: 25745779
- EPR studies of free radicals in A-2058 human melanoma cells treated by valproic acid and 5,7-dimethoxycoumarin. | Zdybel, M., et al. 2014. Acta Pol Pharm. 71: 1066-72. PMID: 25745781
- Nanodiamonds coupled with 5,7-dimethoxycoumarin, a plant bioactive metabolite, interfere with the mitotic process in B16F10 cells altering the actin organization. | Gismondi, A., et al. 2016. Int J Nanomedicine. 11: 557-74. PMID: 26893562
- 5,7-Dimethoxycoumarin prevents chronic mild stress induced depression in rats through increase in the expression of heat shock protein-70 and inhibition of monoamine oxidase-A levels. | Yang, W. and Wang, H. 2018. Saudi J Biol Sci. 25: 253-258. PMID: 29472774
- Qualitative and quantitative analyses of chemical components of Citri Sarcodactylis Fructus from different origins based on UPLC-Q-Exactive Orbitrap-MS and GC-MS. | Ning, J., et al. 2022. Food Sci Nutr. 10: 2057-2070. PMID: 35702295
- Pharmacological insights into Chukrasia velutina bark: Experimental and computer-aided approaches. | Jahan, I., et al. 2022. Animal Model Exp Med. 5: 377-388. PMID: 36047481
- Identification of psoralen, 8-methoxypsoralen, isopimpinellin, and 5,7-dimethoxycoumarin in Pelea anisata H. Mann. | Yoke Marchant, Y., et al. 1985. Contact Dermatitis. 12: 196-9. PMID: 4017567
- The photobinding of 5,7-dimethoxycoumarin to adenovirus type-2 DNA. A method for in vitro mutagenesis. | Jung, V., et al. 1983. Biochim Biophys Acta. 740: 64-72. PMID: 6303427
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IL-23.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
5,7-Dimethoxycoumarin, 1 g | sc-210402 | 1 g | $114.00 |