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5-(Hydroxymethyl)furfuryl Alcohol (CAS 1883-75-6)

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Alternate Names:
2,5-Bis(hydroxymethyl)furan; 2,5-Di(hydroxymethyl)furan
Application:
5-(Hydroxymethyl)furfuryl Alcohol is a DNA polymerase inhibitor n vitro
CAS Number:
1883-75-6
Purity:
≥97%
Molecular Weight:
128.13
Molecular Formula:
C6H8O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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5-(Hydroxymethyl)furfuryl alcohol is a chemical compound that is widely studied in the field of green chemistry and materials science. It serves as a key intermediate in the synthesis of bio-based polymers, resins, and fragrances due to its renewable origins and biodegradable nature. Researchers are interested in 5-(Hydroxymethyl)furfuryl alcohol for its potential to create environmentally friendly materials, and it is also used in the development of furan-based chemicals, which are known for their applications in the production of bioplastics. The hydroxymethyl group provides a reactive site for further chemical modification, making it a versatile monomer for polymerization reactions. In addition, it is investigated for its role in the formulation of adhesives and coatings, where its alcohol functionality can improve adhesion properties and cross-link density.


5-(Hydroxymethyl)furfuryl Alcohol (CAS 1883-75-6) References

  1. Furfural inhibits growth by limiting sulfur assimilation in ethanologenic Escherichia coli strain LY180.  |  Miller, EN., et al. 2009. Appl Environ Microbiol. 75: 6132-41. PMID: 19684179
  2. Evolutionary engineering strategies to enhance tolerance of xylose utilizing recombinant yeast to inhibitors derived from spruce biomass.  |  Koppram, R., et al. 2012. Biotechnol Biofuels. 5: 32. PMID: 22578262
  3. Tolerance of the nanocellulose-producing bacterium Gluconacetobacter xylinus to lignocellulose-derived acids and aldehydes.  |  Zhang, S., et al. 2014. J Agric Food Chem. 62: 9792-9. PMID: 25186182
  4. By-products resulting from lignocellulose pretreatment and their inhibitory effect on fermentations for (bio)chemicals and fuels.  |  van der Pol, EC., et al. 2014. Appl Microbiol Biotechnol. 98: 9579-93. PMID: 25370992
  5. Microwave-assisted chemical pre-treatment of waste sorghum leaves: Process optimization and development of an intelligent model for determination of volatile compound fractions.  |  Rorke, DCS., et al. 2017. Bioresour Technol. 224: 590-600. PMID: 27810249
  6. Utilization of lignocellulosic biomass towards the production of omega-3 fatty acids by the heterotrophic marine microalga Crypthecodinium cohnii.  |  Karnaouri, A., et al. 2020. Bioresour Technol. 303: 122899. PMID: 32028216

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

5-(Hydroxymethyl)furfuryl Alcohol, 1 g

sc-210242
1 g
$211.00

Regarding: 5-(Hydroxymethyl)furfuryl Alcohol sc-210242 What is the working concentration needed to inhibit DNA pol?

Asked by: Loy E
Thank you for your question. We have not tested this chemical for the inhibition of DNA pol so we do not have this information available. We would recommend consulting the primary literature for a reference or a protocol.
Answered by: Technical Support
Date published: 2017-03-28
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Rated 5 out of 5 by from ZhangZhang, Y. et al. (PubMed 21925629) reported the biotransformation of furfural and 5-(Hydroxymethyl)furfural (HMF) by Clostridium acetobutylicum ATCC 824 during butanol fermentation. -SCBT Publication Review
Date published: 2015-02-24
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5-(Hydroxymethyl)furfuryl Alcohol is rated 5.0 out of 5 by 1.
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