Molecular structure of 4-Hydroxybenzyl Isothiocyanate, CAS Number: 2086-86-4
4-Hydroxybenzyl Isothiocyanate (CAS 2086-86-4)
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Alternate Names:
para-Hydroxybenzyl isothiocyanate; 4-Isothiocyanatomethyl-phenol
Application:
4-Hydroxybenzyl Isothiocyanate is an aromatic compound
CAS Number:
2086-86-4
Purity:
≥96%
Molecular Weight:
165.21
Molecular Formula:
C8H7NOS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Hydroxybenzyl Isothiocyanate is a benzylic isothiocyanate compound produced as a metabolic product of 4-hydroxybenzyl glucosinolate. In studies investigating the metabolism of 4-hydroxybenzyl glucosinolate in Sinapis alba seeds, 4-Hydroxybenzyl Isothiocyanate was identified as the initial metabolic product. This substance may act to effectively impede the growth and proliferation of malignant cells. Additionally, it possesses noteworthy anti-inflammatory and antioxidant properties. Its mechanism of action is believed to involve the inhibition of specific enzymes associated with cancer cell growth and inflammation. Furthermore, it has the potential to induce apoptosis, or programmed cell death, in cancer cells.
4-Hydroxybenzyl Isothiocyanate (CAS 2086-86-4) References
- Supercritical fluid chromatography as a method of analysis for the determination of 4-hydroxybenzylglucosinolate degradation products. | Buskov, S., et al. 2000. J Biochem Biophys Methods. 43: 157-74. PMID: 10869674
- Isolation and determination of p-hydroxybenzoylcholine in traditional Chinese medicine Semen sinapis Albae. | Liu, L., et al. 2003. Anal Bioanal Chem. 376: 854-8. PMID: 12811446
- Ionic thiocyanate (SCN-) production from 4-hydroxybenzyl glucosinolate contained in Sinapis alba seed meal. | Borek, V. and Morra, MJ. 2005. J Agric Food Chem. 53: 8650-4. PMID: 16248567
- Herbicidal activity of glucosinolate degradation products in fermented meadowfoam (Limnanthes alba) seed meal. | Stevens, JF., et al. 2009. J Agric Food Chem. 57: 1821-6. PMID: 19170637
- Supercritical fluid chromatography of myrosinase reaction products in ground yellow mustard seed oil. | Choubdar, N., et al. 2010. J Food Sci. 75: C341-5. PMID: 20546392
- Determination of glucosinolates in 19 Chinese medicinal plants with spectrophotometry and high-pressure liquid chromatography. | Hu, Y., et al. 2010. Nat Prod Res. 24: 1195-205. PMID: 20645206
- Brassicaceous seed meals as soil amendments to suppress the plant-parasitic nematodes Pratylenchus penetrans and Meloidogyne incognita. | Zasada, IA., et al. 2009. J Nematol. 41: 221-7. PMID: 22736818
- Effect of white mustard essential oil on inoculated Salmonella sp. in a sauce with particulates. | David, JR., et al. 2013. J Food Prot. 76: 580-7. PMID: 23575118
- Hydrogen sulfide releasing capacity of natural isothiocyanates: is it a reliable explanation for the multiple biological effects of Brassicaceae? | Citi, V., et al. 2014. Planta Med. 80: 610-3. PMID: 24963613
- Effect of white mustard essential oil on the growth of foodborne pathogens and spoilage microorganisms and the effect of food components on its efficacy. | Monu, EA., et al. 2014. J Food Prot. 77: 2062-8. PMID: 25474051
- New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H2S-donor. | Jurkowska, H., et al. 2018. Amino Acids. 50: 699-709. PMID: 29508061
- Novel glucosinolate metabolism in larvae of the leaf beetle Phaedon cochleariae. | Friedrichs, J., et al. 2020. Insect Biochem Mol Biol. 124: 103431. PMID: 32653632
- Bioactivity of brassica seed meals and its compounds as ecofriendly larvicides against mosquitoes. | Flor-Weiler, LB., et al. 2023. Sci Rep. 13: 3936. PMID: 36894606
- Myrosinase-generated isothiocyanate from glucosinolates: isolation, characterization and in vitro antiproliferative studies. | Leoni, O., et al. 1997. Bioorg Med Chem. 5: 1799-806. PMID: 9354235
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Hydroxybenzyl Isothiocyanate, 100 mg | sc-210085 | 100 mg | $398.00 | |||
4-Hydroxybenzyl Isothiocyanate, 500 mg | sc-210085A | 500 mg | $1846.00 | |||
4-Hydroxybenzyl Isothiocyanate, 1 g | sc-210085B | 1 g | $2866.00 |