Date published: 2025-11-20

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(+)-α-Lipoic acid (CAS 1200-22-2)

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Alternate Names:
(3R)-1,2-Dithiolane-3-pentanoic Acid; (R)-(+)-1,2-Dithiolane-3-pentanoic Acid; (+)-1,2-Dithiolane-3-valeric Acid
Application:
(+)-α-Lipoic acid is An antioxidant
CAS Number:
1200-22-2
Molecular Weight:
206.33
Molecular Formula:
C8H14O2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(+)-α-Lipoic Acid (LA) is an indispensable naturally occurring compound. Acting as a cofactor for various enzymes such as pyruvate dehydrogenase, (+)-α-Lipoic Acid facilitates their proper functioning. Although the precise mechanism of action of (+)-α-Lipoic Acid remains incompletely elucidated, it is thought to operate by augmenting the production of glutathion. Furthermore, (+)-α-Lipoic Acid has the ability to hinder the activity of certain enzymes involved in the generation of free radicals.


(+)-α-Lipoic acid (CAS 1200-22-2) References

  1. Lipoic acid metabolism and mitochondrial redox regulation.  |  Solmonson, A. and DeBerardinis, RJ. 2018. J Biol Chem. 293: 7522-7530. PMID: 29191830
  2. Lipoic acid. Kinetics and pluripotent biological properties and derivatives.  |  Theodosis-Nobelos, P., et al. 2021. Mol Biol Rep. 48: 6539-6550. PMID: 34420148
  3. Lipoic Acid Metabolism as a Potential Chemotherapeutic Target Against Plasmodium falciparum and Staphylococcus aureus.  |  Rei Yan, SL., et al. 2021. Front Chem. 9: 742175. PMID: 34805091
  4. Review of lipoic acid: From a clinical therapeutic agent to various emerging biomaterials.  |  Lv, SY., et al. 2022. Int J Pharm. 627: 122201. PMID: 36115465

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(+)-α-Lipoic acid, 5 g

sc-208505
5 g
$156.00